Evidence map›Paper›PMID 39358413›Full record

ArticleCommunications biology2024

Calciprotein particles induce arterial stiffening ex vivo and impair vascular cell function.

Cédric H G Neutel, Callan D Wesley, Cindy van Loo, Céline Civati, Freke Mertens, Michelle Zurek, Anja Verhulst, Isabel Pintelon, Winnok H De Vos, Bart Spronck and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Elevated phosphate levels in CKD - a direct threat for the heart.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
  3. The formation and function of calciprotein particles.Pflugers Archiv : European journal of physiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Cédric H G NeutelLaboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium. cedric.neutel@uantwerpen.be.ORCID 0000-0001-7074-226X
Callan D WesleyLaboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.ORCID 0009-0005-2213-4426
Cindy van LooDepartment of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, the Netherlands.ORCID 0009-0009-0125-1729
Céline CivatiLaboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.
Freke MertensLaboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.
Michelle ZurekLaboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.
Anja VerhulstLaboratory of Pathophysiology, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.ORCID 0000-0002-4533-443X
Isabel PintelonLaboratory of Cell Biology and Histology, University of Antwerp, Antwerp, Belgium.
Winnok H De VosLaboratory of Cell Biology and Histology, University of Antwerp, Antwerp, Belgium.ORCID 0000-0003-0960-6781
Bart SpronckDepartment of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, the Netherlands.ORCID 0000-0003-1076-1922
Lynn RothLaboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.ORCID 0000-0003-1397-1810
Guido R Y De MeyerLaboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.ORCID 0000-0003-3848-8702
Wim MartinetLaboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.
Pieter-Jan GunsLaboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.ORCID 0000-0002-8640-6620

Funding

EC | Horizon 2020 Framework Programme (EU Framework Programme for Research and Innovation H2020) No858070
6 · The paper itself

Abstract

Calciprotein particles (CPPs) are an endogenous buffering system, clearing excessive amounts of Ca

Indexed as

Muscle, Smooth, VascularVascular StiffnessAnimalsAorta, ThoracicGlycosaminoglycansHumansMaleMyocytes, Smooth MuscleRatsVasodilationGlycosaminoglycans

Identifiers

PMID39358413
PMCPMC11447031

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.