Evidence map›Paper›PMID 39359722›Full record

ArticleFrontiers in immunology2024

Differential lipid signaling from CD4

Tayleur D White, Abdulaziz Almutairi, Ying Gai-Tusing, Daniel J Stephenson, Benjamin D Stephenson, Charles E Chalfant, Xiaoyong Lei, Brian Lu, Bruce D Hammock, Teresa P DiLorenzo and 1 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tayleur D WhiteDepartment of Cell, Developmental, and Integrative Biology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Abdulaziz AlmutairiDepartment of Cell, Developmental, and Integrative Biology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Ying Gai-TusingDepartment of Cell, Developmental, and Integrative Biology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Daniel J StephensonCancer Biology Program, University of Virginia National Cancer Institute (UVA NCI) Comprehensive Cancer Center, University of Virginia-School of Medicine, Charlottesville, VA, United States.
Benjamin D StephensonCancer Biology Program, University of Virginia National Cancer Institute (UVA NCI) Comprehensive Cancer Center, University of Virginia-School of Medicine, Charlottesville, VA, United States.
Charles E ChalfantCancer Biology Program, University of Virginia National Cancer Institute (UVA NCI) Comprehensive Cancer Center, University of Virginia-School of Medicine, Charlottesville, VA, United States.
Xiaoyong LeiDepartment of Cell, Developmental, and Integrative Biology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Brian LuComprehensive Diabetes Center, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
Bruce D HammockEntomology and Nematology and Comprehensive Cancer Center, University of California, Davis, Davis, CA, United States.
Teresa P DiLorenzoDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, United States.
Sasanka RamanadhamDepartment of Cell, Developmental, and Integrative Biology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.

Funding

Workshop on Environmental Technology Transfer and EntrepreneurshipP42ES004699 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI YOUNG, THOMAS MICHAEL · 1987 to 2021
$50.1M
Supplement for bioactive lipids as effectors and indicators of the deleterious effects of human healthR35ES030443 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MORISSEAU, CHRISTOPHE HP · 2019 to 2025
$5.8M
The roles of ceramide and its derivatives in A. phagocytophilum pathogenesisR01AI139072 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI CHARLES E. CHALFANT, Jason A Carlyon · 2018 to 2026
$5.7M
Training Program in Cell, Molecular, and Developmental BiologyT32GM008111 · NIGMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI YODER, BRADLEY K. · 1985 to 2022
$5.4M
CALCIUM-INDEPENDENT PLA2BETA IN BETA-CELL APOPTOSISR01DK069455 · NIDDK · WASHINGTON UNIVERSITY · PI RAMANADHAM, SASANKA · 2004 to 2013
$2.7M
iPLA2beta-mediated alternative splicing and -cell death in type 1 diabetesR01DK126444 · NIDDK · UNIVERSITY OF VIRGINIA · PI CHALFANT, CHARLES E., EIZIRIK, DECIO LAKS · 2021 to 2024
$2.0M
Contribution of β-Cell- & Immune Cell-Derived Lipids to β-Cell Death and DiabetesR01DK110292 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RAMANADHAM, SASANKA · 2016 to 2019
$1.7M
The role of ceramide kinase in mitophagyR01GM137578 · NIGMS · UNIVERSITY OF VIRGINIA · PI CHALFANT, CHARLES E. · 2020 to 2023
$1.3M
Exploiting iPLA2β-modified macrophages as immunotherapy for T1DR21AI169214 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RAMANADHAM, SASANKA · 2022 to 2023
$397k
BLRD VA I01 BX001792BLRD VA I01 BX006063BLRD VA IK6 BX004603NIAID NIH HHS R01 AI139072NIAID NIH HHS R21 AI169214NIDDK NIH HHS R01 DK069455NIDDK NIH HHS R01 DK110292NIDDK NIH HHS R01 DK126444NIEHS NIH HHS P42 ES004699NIEHS NIH HHS R35 ES030443NIGMS NIH HHS R01 GM137578NIGMS NIH HHS T32 GM008111
6 · The paper itself

Abstract

Introduction: We reported that Ca Methods: CD4 Results: In mice receiving only Discussion: These findings suggest that differential select iDL signaling in CD4

Indexed as

CD4-Positive T-LymphocytesCD8-Positive T-LymphocytesDiabetes Mellitus, Type 1Mice, Inbred NODSignal TransductionAnimalsFemaleGroup VI Phospholipases A2Insulin-Secreting CellsLipid MetabolismMiceMice, SCIDGroup VI Phospholipases A2Pla2g6 protein, mouseadoptive transferflow cytometryislet microscopylipidomicslipid signalingT-lymphocytestype 1 diabetes

Identifiers

PMID39359722
PMCPMC11445035

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.