Evidence map›Paper›PMID 39360042›Full record

ArticleCureus2024

Analyzing the Bioactivity of a Novel Bone Cement: An In Vitro Study.

Janani Balachandran, Kalai Vani, Venkatesh Alagarsamy, Pooraninagalakshmi J, Jembulingam Sabarathinam

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Janani BalachandranDepartment of Conservative Dentistry and Endodontics, Sree Balaji Dental College & Hospital, Chennai, IND.
Kalai VaniDepartment of Conservative Dentistry and Endodontics, Sree Balaji Dental College & Hospital, Chennai, IND.
Venkatesh AlagarsamyDepartment of Conservative Dentistry and Endodontics, Sree Balaji Dental College & Hospital, Chennai, IND.
Pooraninagalakshmi JDepartment of Conservative Dentistry and Endodontics, Sree Balaji Dental College & Hospital, Chennai, IND.
Jembulingam SabarathinamDepartment of Conservative Dentistry and Endodontics, Sree Balaji Dental College & Hospital, Chennai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo analyze the effect of bioactive bone cement (BBC) placed in a phosphate buffer saline solution in comparison to mineral trioxide aggregate (MTA). METHODOLOGY: Ten samples each of BBC (group 1) and MTA (group 2) were prepared and stored in a phosphate buffer saline solution. After three days of storage, white precipitates were formed on the surface of the samples. The solution with precipitates from each sample was analyzed for the presence of calcium and phosphate ions with coupled plasma atomic spectroscopy.

resultsBBC showed a significant amount of calcium and phosphate release after a seven-day storage period in phosphate buffer saline solution. Calcium release was significantly higher in group 1 (MTA) (p < 0.001) compared to that in group 2 (BBC), while group 2 (BBC) (p < 0.001) exhibited greater phosphate release compared to group 1 (MTA).

conclusionBBC (group 2) retains its bioactivity when it comes into contact with a stimulated oral environment (STF). This demonstrates that BBC is bioactive in a simulated oral environment. Moreover, it retained good handling properties and could be easily manipulated into a dough form. Clinically, in cases of apical surgery, internal resorption or perforation repair where material placement poses difficulty, BBC will prove to be beneficial.

Indexed as

bioactivebone cementhydroxyapatiteinductively coupled plasma atomic spectoscopymineral trioxide aggregate (mta)

Identifiers

PMID39360042
PMCPMC11445635

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.