ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2025
REM sleep-related bradyarrhythmia syndrome.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Sleep, Neural Circulatory Control, and Cardiovascular Disease: A Mechanistic Review.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- REM Sleep-Associated Asystole.JACC. Case reports · 2026Article
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Authors and funding
7 authors.
Funding
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Abstract
Rapid eye movement sleep-related bradyarrhythmia syndrome is a rare condition marked by abnormal sinus arrest or atrioventricular conduction disturbance blocks during rapid eye movement sleep unassociated with sleep-disordered breathing. We present a case of a young male without a cardiovascular history exhibiting pauses of up to 9.7 seconds during polysomnography. Initially referred for suspected obstructive sleep apnea due to nocturnal awakenings with shortness of breath, confusion, and dizziness. Polysomnography results were unremarkable apart from electrocardiogram findings revealing prolonged sinus pauses related to rapid eye movement sleep. Evaluation via extended 14-day patch monitor revealed an overall normal sinus rhythm with the lowest heart rate recorded at 14 beats per minute and 412 pauses exceeding 2 seconds, with the longest pause lasting 12.5 seconds during nocturnal hours. A permanent pacemaker was considered, but after shared decision making with the patient, the decision was to continue monitoring without any intervention. CITATION: Perez K, Shah M, Sridharan A, et al. REM sleep-related bradyarrhythmia syndrome.
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Registered trials
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