Evidence map›Paper›PMID 39361263›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

An AI Agent for Fully Automated Multi-Omic Analyses.

Juexiao Zhou, Bin Zhang, Guowei Li, Xiuying Chen, Haoyang Li, Xiaopeng Xu, Siyuan Chen, Wenjia He, Chencheng Xu, Liwei Liu and 1 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Review
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  16. Review
  17. A Framework for Autonomous AI-Driven Drug Discovery.bioRxiv : the preprint server for biology · 2026
    Article
  18. Biomechanics-Driven 3D Architecture Inference from Histology Using CellSqueeze3D.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Juexiao ZhouComputer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.ORCID 0000-0002-6739-6236
Bin ZhangComputer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.
Guowei LiLaboratory of Health Intelligence, Huawei Technologies Co., Ltd, Shenzhen, 210000, China.
Xiuying ChenComputer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.
Haoyang LiComputer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.
Xiaopeng XuComputer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.
Siyuan ChenComputer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.
Wenjia HeComputer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.
Chencheng XuComputer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.
Liwei LiuAdvanced Computing and Storage Laboratory, Central Research Institute, 2012 Laboratories, Huawei Technologies Co., Ltd, Nanjing, Jiangsu, 210000, China.
Xin GaoComputer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.

Funding

Global Collaborative Research, King Abdullah University of Science and Technology FCC/1/1976-44-01Global Collaborative Research, King Abdullah University of Science and Technology FCC/1/1976-45-01Global Collaborative Research, King Abdullah University of Science and Technology REI/1/0018-01-01Global Collaborative Research, King Abdullah University of Science and Technology REI/1/4940-01-01Global Collaborative Research, King Abdullah University of Science and Technology REI/1/5202-01-01Global Collaborative Research, King Abdullah University of Science and Technology REI/1/5234-01-01Global Collaborative Research, King Abdullah University of Science and Technology REI/1/5289-01-01Global Collaborative Research, King Abdullah University of Science and Technology REI/1/5404-01-01Global Collaborative Research, King Abdullah University of Science and Technology REI/1/5414-01-01Global Collaborative Research, King Abdullah University of Science and Technology RGC/3/4816-01-01
6 · The paper itself

Abstract

With the fast-growing and evolving omics data, the demand for streamlined and adaptable tools to handle bioinformatics analysis continues to grow. In response to this need, Automated Bioinformatics Analysis (AutoBA) is introduced, an autonomous AI agent designed explicitly for fully automated multi-omic analyses based on large language models (LLMs). AutoBA simplifies the analytical process by requiring minimal user input while delivering detailed step-by-step plans for various bioinformatics tasks. AutoBA's unique capacity to self-design analysis processes based on input data variations further underscores its versatility. Compared with online bioinformatic services, AutoBA offers multiple LLM backends, with options for both online and local usage, prioritizing data security and user privacy. In comparison to ChatGPT and open-source LLMs, an automated code repair (ACR) mechanism in AutoBA is designed to improve its stability in automated end-to-end bioinformatics analysis tasks. Moreover, different from the predefined pipeline, AutoBA has adaptability in sync with emerging bioinformatics tools. Overall, AutoBA represents an advanced and convenient tool, offering robustness and adaptability for conventional multi-omic analyses.

Indexed as

Artificial IntelligenceComputational BiologyAutomationHumansMultiomicsSoftwareagentbioinformaticslarge language modelomics analysis

Identifiers

PMID39361263
PMCPMC11600294

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.