Evidence map›Paper›PMID 39362885›Full record

ReviewNature reviews. Disease primers2024

Scabies.

Deepani D Fernando, Kate E Mounsey, Charlotte Bernigaud, Nuzhat Surve, Guadalupe E Estrada Chávez, Roderick J Hay, Bart J Currie, Olivier Chosidow, Katja Fischer

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Disease primers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
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  17. Rising scabies incidence in Spain: a retrospective observational analysis of four national data sources, 2011 to 2023.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Observational
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Deepani D FernandoScabies Laboratory, Infection and Inflammation Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.ORCID http://orcid.org/0000-0002-3079-0985
Kate E MounseySchool of Health, University of the Sunshine Coast, Sippy Downs, Queensland, Australia.ORCID http://orcid.org/0000-0003-0579-9424
Charlotte BernigaudResearch Group Dynamic, EA7380, Faculté de Santé de Créteil, USC ANSES, Université Paris-Est Créteil, Créteil, France.
Nuzhat SurveDepartment of Microbiology, Seth G S Medical College and KEM Hospital, Parel, Mumbai, India.ORCID http://orcid.org/0009-0007-6515-4624
Guadalupe E Estrada ChávezState Institute of Cancer "Dr. Arturo Beltrán Ortega", Faculty of Medicine, Universidad Autónoma de Guerrero, Community Dermatology Mexico, Acapulco, Guerrero, Mexico.
Roderick J HaySt Johns Institute of Dermatology, King's College London, London, UK.
Bart J CurrieGlobal and Tropical Health, Menzies School of Health Research, Charles Darwin University and Royal Darwin Hospital, Darwin, Northern Territory, Australia.ORCID http://orcid.org/0000-0002-8878-8837
Olivier ChosidowHôpital Universitaire La Pitié-Salpêtrière, AP-HP, Paris, France.ORCID http://orcid.org/0000-0002-8400-4310
Katja FischerScabies Laboratory, Infection and Inflammation Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia. Katja.Fischer@qimrberghofer.edu.au.ORCID http://orcid.org/0000-0003-3408-3337

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scabies is one of the most common and highest-burden skin diseases globally. Estimates suggest that >200 million people worldwide have scabies at any one time, with an annual prevalence of 455 million people, with children in impoverished and overcrowded settings being the most affected. Scabies infection is highly contagious and leads to considerable morbidity. Secondary bacterial infections are common and can cause severe health complications, including sepsis or necrotizing soft-tissue infection, renal damage and rheumatic heart disease. There is no vaccine or preventive treatment against scabies and, for the past 30 years, only few broad-spectrum antiparasitic drugs (mainly topical permethrin and oral ivermectin) have been widely available. Treatment failure is common because drugs have short half-lives and do not kill all developmental stages of the scabies parasite. At least two consecutive treatments are needed, which is difficult to achieve in resource-poor and itinerant populations. Another key issue is the lack of a practical, rapid, cheap and accurate diagnostic tool for the timely detection of scabies, which could prevent the cycle of exacerbation and disease persistence in communities. Scabies control will require a multifaceted approach, aided by improved diagnostics and surveillance, new treatments, and increased public awareness.

Indexed as

IvermectinScabiesAntiparasitic AgentsHumansPermethrinPrevalenceAntiparasitic AgentsIvermectinPermethrin

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.