Evidence map›Paper›PMID 39363010›Full record

ArticleScientific reports2024

Proteomic analysis of plasma-derived extracellular vesicles: pre- and postprandial comparisons.

Alejandra P Garza, Elisa Wider-Eberspächer, Lorena Morton, Marco van Ham, Éva Pállinger, Edit I Buzás, Lothar Jänsch, Ildiko R Dunay

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Plasma-Derived Extracellular Vesicle Proteomics.Journal of proteome research · 2025
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alejandra P Garza *Institute of Inflammation and Neurodegeneration, Medical Faculty, Otto-Von-Guericke University, Magdeburg, Germany.
Elisa Wider-Eberspächer *Institute of Inflammation and Neurodegeneration, Medical Faculty, Otto-Von-Guericke University, Magdeburg, Germany.
Lorena MortonInstitute of Inflammation and Neurodegeneration, Medical Faculty, Otto-Von-Guericke University, Magdeburg, Germany.
Marco van HamCellular Proteome Research Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Éva PállingerDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary.
Edit I BuzásDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary.
Lothar JänschCellular Proteome Research Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Ildiko R DunayInstitute of Inflammation and Neurodegeneration, Medical Faculty, Otto-Von-Guericke University, Magdeburg, Germany. ildiko.dunay@med.ovgu.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) are key in intercellular communication, carrying biomolecules like nucleic acids, lipids, and proteins. This study investigated postprandial characteristics and proteomic profiles of blood-derived EVs in healthy individuals. Twelve participants fasted overnight before baseline assessments. After consuming a controlled isocaloric meal, EVs were isolated for proteomic and flow cytometric analysis. Plasma triacylglyceride levels confirmed fasting completion, while protein concentrations in plasma and EVs were monitored for postprandial stability. Proteomic analysis identified upregulated proteins related to transport mechanisms and epithelial/endothelial functions postprandially, indicating potential roles in physiological responses to nutritional intake. Enrichment analyses revealed vesicle-related pathways and immune system processes. Flow cytometry showed increased expression of CD324 on CD9

Indexed as

Extracellular VesiclesPostprandial PeriodProteomicsAdultFastingFemaleHumansMaleProteomeYoung AdultProteomeExtracellular vesiclesFastingLiquid biopsyPlasmaPostprandialProteomics

Identifiers

PMID39363010
PMCPMC11450010

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.