Evidence map›Paper›PMID 39363489›Full record

ArticleNeurospine2024

The Clinical Outcomes of Cervical Spine Chordoma: A Nationwide Multicenter Retrospective Study.

Hangeul Park, Yunhee Choi, Sungjoon Lee, Sun-Ho Lee, Eun-Sang Kim, Sun Woo Jang, Jin Hoon Park, Yunseong Cho, Giwuk Jang, Yoon Ha and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurospine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Hangeul ParkDepartment of Neurosurgery, Seoul National University Hospital, Seoul, Korea.
Yunhee ChoiDivision of Medical Statistics, Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Korea.
Sungjoon LeeDepartment of Neurosurgery, Samsung Medical Center, Seoul, Korea.
Sun-Ho LeeDepartment of Neurosurgery, Samsung Medical Center, Seoul, Korea.
Eun-Sang KimDepartment of Neurosurgery, Samsung Medical Center, Seoul, Korea.
Sun Woo JangDepartment of Neurosurgery, Asan Medical Center, Seoul, Korea.
Jin Hoon ParkDepartment of Neurosurgery, Asan Medical Center, Seoul, Korea.
Yunseong ChoDepartment of Neurosurgery, Severance Hospital, Seoul, Korea.
Giwuk JangDepartment of Neurosurgery, Severance Hospital, Seoul, Korea.
Yoon HaDepartment of Neurosurgery, Severance Hospital, Seoul, Korea.
Yun-Sik DhoNeuro-Oncology Clinic, National Cancer Center, Goyang, Korea.
Heon YooNeuro-Oncology Clinic, National Cancer Center, Goyang, Korea.
Sung Uk LeeCenter for Proton Therapy, National Cancer Center, Goyang, Korea.
Seung-Ho SeoDepartment of Neurosurgery, Seoul National University Bundang Hospital, Seongnam, Korea.
Ki-Jeong KimDepartment of Neurosurgery, Seoul National University Bundang Hospital, Seongnam, Korea.
Seil SohnDepartment of Neurosurgery, CHA Bundang Medical Center, Seongnam, Korea.
Chun Kee ChungNeuroscience Research Institute, Seoul National University College of Medicine, Seoul, Korea.

Funding

Korean Spine Oncology Research Society 2023-004
6 · The paper itself

Abstract

objectiveChordoma, a rare malignant tumor originating from embryonal notochord remnants, exhibits high resistance to conventional treatments, making surgical resection imperative. However, the factors influencing prognosis specifically for cervical spine chordoma have not been clearly identified. We investigate the prognosis of cervical spine chordoma with factors influential in a nationwide multicenter retrospective study.

methodsThis study included all patients diagnosed with cervical spine chordoma at 7 tertiary referral centers from January 1998 to March 2023, excluding those with clivus and thoracic spine chordomas extending into the cervical spine. Local recurrence (LR) was identified through follow-up magnetic resonance imaging, either as reappearance in completely resected tumors or regrowth in residual tumors. The study assessed LR and overall survival, analyzing factors influencing LR and death.

resultsForty-five patients with cervical spine chordoma had a mean age of 46.4 years. Over a median follow-up of 52 months, LR and distant metastasis were observed in 21 (46.7%) and 4 patients (8.9%), respectively, and 16 patients (36%) were confirmed dead. The 5-year and 10-year cumulative LR rates were 51.3% and 60%, respectively, while the 5-year and 10-year survival rates were 82% and 53%. Age was the only significant factor affecting mortality (hazard ratio, 1.04; 95% confidence interval, 1.04-1.07; p=0.015). Notably, the degree of resection and adjuvant therapy did not statistically significantly impact local tumor control and mortality.

conclusionThis study, the largest multicenter retrospective analysis of cervical spine chordoma in Korea, identified age as the only factor significantly affecting patient survival.

Indexed as

Cervical spineChordomaRecurrenceSurgerySurvival rateTreatment outcome

Identifiers

PMID39363489
PMCPMC11456934

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.