Evidence mapPaperPMID 39364693Full record

Trial reportDrug and alcohol review2025

Vaping to quit smoking: Qualitative study of people receiving opioid agonist treatment.

Kypros Kypri, Emma Austin, Melissa Jackson, Kirsten Wright, Amanda Shui, Andrew Li, Vinogi Sathasivam, Billie Bonevski, Adrian J Dunlop

Abstract readClinical Trial, Phase IVEquivalence TrialMulticenter Study
In one paragraph

Trial report in Drug and alcohol review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kypros KypriDrug and Alcohol Clinical Services, Hunter New England Local Health District, Newcastle, Australia.ORCID 0000-0002-9657-9904
Emma AustinDrug and Alcohol Clinical Services, Hunter New England Local Health District, Newcastle, Australia.
Melissa JacksonDrug and Alcohol Clinical Services, Hunter New England Local Health District, Newcastle, Australia.ORCID 0000-0002-1491-6218
Kirsten WrightSchool of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, Australia.
Amanda ShuiSchool of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, Australia.
Andrew LiSchool of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, Australia.
Vinogi SathasivamSchool of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, Australia.
Billie BonevskiFlinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, Adelaide, Australia.
Adrian J DunlopDrug and Alcohol Clinical Services, Hunter New England Local Health District, Newcastle, Australia.ORCID 0000-0003-2394-5966

Funding

NSW Health
6 · The paper itself

Abstract

introductionMost patients receiving opioid agonist treatment (OAT) smoke tobacco. Approved cessation interventions are less effective in this group than the wider population. We investigated how people on OAT experience nicotine vaping to quit smoking.

methodsPatients on OAT randomised to the vaping arm of a smoking cessation trial were invited to participate in structured interviews incorporating broad pre-determined themes. A qualitative descriptive approach employing template analysis was used. Four authors coded transcripts, discussed discrepancies, modified the template using both inductive and deductive approaches. Authors made explicit their starting orientations and independent authors sought disconfirmatory data in a subsequent round of analysis.

resultsFour women and eight men (median age 44 years) participated, including four who identified as Aboriginal. Participants reported vaping as cheaper, more acceptable and less stigmatising than smoking but expressed concerns about ongoing accessibility due to the Australian prescription access model. Some found it technically challenging at first, but not more so than standard nicotine replacement therapies. Participants gave accounts of craving and withdrawal experiences, including supplementary use of nicotine patches, and compulsions to vape frequently and intensely, potentially indicating need for higher nicotine dosage. Participants generally reported that vaping helped them quit smoking, though some worried about swapping nicotine addictions. Others were glad to be using a lower-risk alternative. DISCUSSION AND

conclusionsThis group reported varied experiences of nicotine vaping but were mainly optimistic that it could help them and others quit smoking. This was despite initial nicotine cravings and concerns about remaining addicted long-term.

Indexed as

Analgesics, OpioidSmoking CessationVapingAdultAustraliaFemaleHumansMaleMiddle AgedQualitative ResearchTobacco Use Cessation DevicesAnalgesics, Opioidnicotineopioid agonist treatmentpatient experiencesmoking cessationvaping

Identifiers

PMID39364693
PMCPMC11742974

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.