Evidence map›Paper›PMID 39365864›Full record

ArticleScience advances2024

BCL-X

Andrew S Judd, Bhupinder Bawa, Wayne R Buck, Zhi-Fu Tao, Yingchun Li, Michael J Mitten, Milan Bruncko, Nathaniel Catron, George Doherty, Kenneth R Durbin and 35 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. BCL-2 and BCL-xL in Cancer: Regulation, Function, and Therapeutic Targeting.International journal of molecular sciences · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

45 authors.

Andrew S JuddAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0000-0003-2562-8841
Bhupinder BawaAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0000-0001-9891-4078
Wayne R BuckAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0000-0002-0698-2178
Zhi-Fu TaoAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0000-0001-5040-2444
Yingchun LiAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0000-0002-9428-7780
Michael J MittenAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
Milan BrunckoAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
Nathaniel CatronAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
George DohertyAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0006-2283-7962
Kenneth R DurbinAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0000-0001-7163-4877
Brian EnrightAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
Robin FreyAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0007-6116-7436
Deanna HaaschAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0004-6805-0730
Sandra HamanAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0001-7556-9045
Anthony R HaightAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0005-5300-7163
Tracy A HenriquesAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
James HolmsAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0002-7007-3822
Kamel IzeradjeneAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
Russell A JudgeAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0000-0001-5917-9269
Gary J JenkinsAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0004-4585-8542
Aaron KunzerAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
Joel D LeversonAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
Ruth L MartinAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0000-0002-0318-5325
Diya MitraAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0003-4478-6594
Scott MittelstadtAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0005-7554-2618
Lorne NelsonAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0004-8825-209X
Paul NimmerAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0003-4804-4555
Joann PalmaAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0008-9500-5002
Richard PetersonAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0001-3750-817X
Darren C PhillipsAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
Sherry L RalstonAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0005-4664-4025
Saul H RosenbergAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
Xiaoqiang ShenAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0000-0002-2746-4484
Xiaohong SongAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
Kedar S VaidyaAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0000-0001-6600-2648
Xilu WangAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
Jin WangAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0000-0001-5420-5704
Yu XiaoAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
Haichao ZhangAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
Xinxin ZhangAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0009-4032-0272
Eric A BlommeAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0000-0001-5657-7667
Erwin R BoghaertAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.
John C KalvassAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0000-0003-4414-2804
Andrew PhillipsAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0008-0826-236X
Andrew J SouersAbbVie Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA.ORCID 0009-0002-5965-0633

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overexpression of the antiapoptotic protein B-cell lymphoma-extra large (BCL-X

Indexed as

bcl-X ProteinImmunoconjugatesXenograft Model Antitumor AssaysAnimalsAntineoplastic AgentsCell Line, TumorHumansMiceSmall Molecule LibrariesAntineoplastic AgentsBCL2L1 protein, humanbcl-X ProteinImmunoconjugatesSmall Molecule Libraries

Identifiers

PMID39365864
PMCPMC11451551

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.