Evidence map›Paper›PMID 39367972›Full record

ArticleMikrochimica acta2024

Detection of pathogenic gram-negative bacteria using an antimicrobial peptides-modified bipolar electrode-electrochemiluminescence platform.

Lei Ji, Fengyang Wang, Yan Qi, Fanglin Qiao, Xiaohui Xiong, Yuanjian Liu

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lei JiColl Food Sci & Light Ind, Nanjing Tech University, Nanjing, 211800, China.
Fengyang WangColl Food Sci & Light Ind, Nanjing Tech University, Nanjing, 211800, China.
Yan QiColl Food Sci & Light Ind, Nanjing Tech University, Nanjing, 211800, China.
Fanglin QiaoColl Food Sci & Light Ind, Nanjing Tech University, Nanjing, 211800, China.
Xiaohui XiongColl Food Sci & Light Ind, Nanjing Tech University, Nanjing, 211800, China.
Yuanjian LiuColl Food Sci & Light Ind, Nanjing Tech University, Nanjing, 211800, China. lucias_cumt@163.com.

Funding

the Postgraduate Research and Practice Innovation Programme Projects of Jiangsu SJCX24_0497
6 · The paper itself

Abstract

Real-time, label-free detection of gram-negative bacteria with high selectivity and sensitivity is demonstrated using a bipolar electrode-electrochemiluminescence (BPE-ECL) platform. This platform utilizes anode luminescence and cathode modification of antimicrobial peptides (AMPs) to effectively capture bacteria. Magainin I, basic AMP from Xenopus skin, boasting an α-helix structure, exhibits a preferential affinity for the surface of gram-negative pathogens. The covalent attachment of the peptide's C-terminal carboxylic acid to the free amines of a previously thiolated linker ensures its secure immobilization onto the surface of the interdigitated gold-plated cathode of BPE. The AMP-modified BPE sensor, when exposed to varying concentrations of gram-negative bacteria, produces reproducible ECL intensities, allowing for the detection of peptide-bacteria interactions within the range 1 to 10

Indexed as

Electrochemical TechniquesElectrodesLuminescent MeasurementsAnimalsAntimicrobial Cationic PeptidesAntimicrobial PeptidesBiosensing TechniquesGram-Negative BacteriaLimit of DetectionMagaininsXenopus ProteinsAntimicrobial Cationic PeptidesAntimicrobial Peptidesmagainin 1 peptide, XenopusMagaininsXenopus ProteinsAMPBacterial sensingBioelectronic sensorsElectroluminescence

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.