Evidence map›Paper›PMID 39370461›Full record

Trial reportLasers in medical science2024

Dose-dependent effects of transcranial photobiomodulation on brain temperature in patients with major depressive disorder: a spectroscopy study.

Akila Weerasekera, David Richer Araujo Coelho, Eva-Maria Ratai, Katherine Anne Collins, Aura Maria Hurtado Puerto, Luis De Taboada, Maia Beth Gersten, Julie A Clancy, Matthew J Hoptman, Molly Kennedy Irvin and 6 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Lasers in medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. [A simulation study of photothermal effects in transcranial photobiomodulation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Akila Weerasekera *Athinoula A. Martinos Center for Biomedical Imaging, 149 13th Street, Charlestown, Boston, MA, 2612, USA. aweerasekera@mgh.harvard.edu.ORCID http://orcid.org/0000-0003-0446-7604
David Richer Araujo Coelho *Division of Neuropsychiatry and Neuromodulation, Massachusetts General Hospital (MGH), Boston, MA, USA.ORCID http://orcid.org/0000-0003-4217-2399
Eva-Maria RataiAthinoula A. Martinos Center for Biomedical Imaging, 149 13th Street, Charlestown, Boston, MA, 2612, USA.
Katherine Anne CollinsNathan Kline Institute (NKI), Orangeburg, NY, USA.
Aura Maria Hurtado PuertoDivision of Neuropsychiatry and Neuromodulation, Massachusetts General Hospital (MGH), Boston, MA, USA.
Luis De TaboadaNeuroThera, New York City, NY, USA.
Maia Beth GerstenDivision of Neuropsychiatry and Neuromodulation, Massachusetts General Hospital (MGH), Boston, MA, USA.
Julie A ClancyDivision of Neuropsychiatry and Neuromodulation, Massachusetts General Hospital (MGH), Boston, MA, USA.
Matthew J HoptmanNathan Kline Institute (NKI), Orangeburg, NY, USA.
Molly Kennedy IrvinNathan Kline Institute (NKI), Orangeburg, NY, USA.
Allison Mary SparpanaNathan Kline Institute (NKI), Orangeburg, NY, USA.
Elizabeth F SullivanNathan Kline Institute (NKI), Orangeburg, NY, USA.
Xiaotong SongNew York University (NYU) School of Medicine, New York City, NY, USA.
Arwa AdibNew York University (NYU) School of Medicine, New York City, NY, USA.
Paolo CassanoDivision of Neuropsychiatry and Neuromodulation, Massachusetts General Hospital (MGH), Boston, MA, USA.ORCID http://orcid.org/0000-0003-0225-199X
Dan Vlad IosifescuNew York University (NYU) School of Medicine, New York City, NY, USA.ORCID http://orcid.org/0000-0002-2512-2835

Funding

Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression (TRIADE)R33MH122647 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CASSANO, PAOLO, IOSIFESCU, DAN VLAD · 2023 to 2025
$2.4M
Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression (TRIADE)R61MH122647 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CASSANO, PAOLO, IOSIFESCU, DAN VLAD · 2020 to 2021
$1.7M
NIH HHS R33 MH122647NIH HHS R61 MH122647
6 · The paper itself

Abstract

This study aimed to evaluate the dose-dependent brain temperature effects of transcranial photobiomodulation (t-PBM). Thirty adult subjects with major depressive disorder were randomized to three t-PBM sessions with different doses (low: 50 mW/cm

Indexed as

BrainLow-Level Light TherapyMajor Depressive DisorderAdultBody TemperatureDose-Response Relationship, RadiationFemaleHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMiddle AgedProton Magnetic Resonance SpectroscopyYoung AdultBrain temperatureMagnetic resonance imagingNear-infrared lightPhotobiomodulationSpectroscopyThermometry

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.