ReviewCurrent health sciences journal
Cognitive Decline in Ageing and Disease: Risk factors, Genetics and Treatments.
Review in Current health sciences journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Challenges and Strategies of Informal Caregivers in Medication Management for Older Adults: A Mixed Method Systematic Review.International journal of older people nursing · 2026Pooled it
- Investigating the impact of migraine on short-term and working memory: a systematic review and meta-analysis.Journal of neurology · 2026Pooled it
- Exploring molecular frameworks for modulating NLRP3-driven neuroinflammation in Alzheimer's disease.Molecular diversity · 2026Review
- Associations of Social Support, Loneliness, and Physical Activity with Cognitive Function in Older Adults with Mild Cognitive Impairment.Journal of clinical medicine · 2026Article
- Hippocampal snRNA-seq in Collaborative Cross reveals molecular signatures of cognitive resilience independent of chronological aging.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Agricultural Injuries With Dementia: Double Whammy?American journal of industrial medicine · 2026Article
- Roles of Lcn2 and neuroinflammation in a scopolamine-induced cognitive impairment animal model: implication of the NLRP3 inflammasome pathway.Genes & genomics · 2026Article
- Resting heart rate and cognitive function in ageing: Insights from a secondary data analysis.GeroScience · 2026Article
- Exercise-associated changes in leptin and irisin relate to cognitive function in older adults stratified by cognitive impairment.Scientific reports · 2026Article
- Cognitive and fine motor performance in people above 65 years of age with and without HIV.Scientific reports · 2026Article
- Article
- Oral microbiome diversity shapes the association between leisure-time physical activity and cognitive function among older adults.iScience · 2026Article
- Review
- Editorial: Mechanisms and interventions for enhancing cognitive reserve in aging populations.Frontiers in neuroscience · 2026Article
- Risk Factors and Annual Rates of Cognitive Decline in Elderly Mild Cognitive Impairment: A Retrospective Cohort Study.Neuropsychiatric disease and treatment · 2026Article
- Impact of metformin use on neurocognitive functions in older people: a systematic review and meta-analysis.Dementia & neuropsychologia · 2026Review
- Associations Between Serum Selenium, Zinc, and Copper Levels and Cognitive Function in the Elderly.Nutrients · 2025Article
- Oroxylum indicum ameliorates D-galactose-induced aging related memory impairments via enhancing rat hippocampal neurogenesis.Scientific reports · 2025Article
- Single-cell, multi-region profiling of the macaque brain across the lifespan.bioRxiv : the preprint server for biology · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aging is the primary risk factor for cognitive decline, impacting multiple cognitive domains and significantly elevating the risk of conditions such as mild cognitive impairment and dementia. In addition to aging, several diseases contribute to cognitive decline. Alzheimer's disease, a progressive neurodegenerative disorder, leads to the loss of neurons and synapses in the brain, resulting in a profound decline in cognitive abilities and functional capacity. Several studies provide compelling evidence that modifiable lifestyle factors play a crucial role in influencing cognitive health. Adopting healthier behaviors has been shown to significantly reduce the risk of cognitive decline. Genetic factors also play a crucial role in cognitive decline, with several genes being identified that influence the risk of developing conditions like Alzheimer's disease and other dementias. Long-term use of opioids and cocaine is also associated with cognitive decline, affecting functions such as memory and executive processes. Understanding the factors contributing to cognitive decline in aging and disease is essential for developing strategies to mitigate its impact. The drugs available to treat patients with cognitive decline due to advanced aging and drug abuse are also summarize.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.