Evidence map›Paper›PMID 39371854›Full record

ReviewCureus2024

Heart Transplantation and Left Ventricular Assist Devices: Long-Term Prognosis and Effects on Mental Health.

Hairya Ajaykumar Lakhani, Lenin Steve Lizarzaburo Penafiel, Marc Fakhoury, Melinda Seide, Patricio Xavier Duran S, Jia Whei See, Damandeep Kaur Dhillon, Shivendra Shah, Aysha Mohsin Khan, Marthand Nimmagadda and 2 more

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hairya Ajaykumar LakhaniInternal Medicine, Smt. B. K. Shah Medical Institute and Research Center, Vadodara, IND.
Lenin Steve Lizarzaburo PenafielInternal Medicine, Universidad de Las Americas, Quito, ECU.
Marc FakhouryCardiology, Saint Joseph University of Beirut, Beirut, LBN.
Melinda SeideInternal Medicine, St. George's University School of Medicine, St. George's, GRD.
Patricio Xavier Duran SInternal Medicine, Universidad de Cuenca, Cuenca, ECU.
Jia Whei SeeInternal Medicine, Universitas Sriwijaya, Kota Palembang, IDN.
Damandeep Kaur DhillonInternal Medicine, St. James School of Medicine, St. Vincent, VCT.
Shivendra ShahInternal Medicine, Nepalgunj Medical College, Nepalgunj, NPL.
Aysha Mohsin KhanInternal Medicine, Karuna Medical College, Palakkad, IND.
Marthand NimmagaddaInternal Medicine, American University of Barbados, Bridgetown, BRB.
Thirumalasetty SusmithaInternal Medicine, Odessa National Medical University, Odessa, UKR.
Manju RaiBiotechnology, Shri Venkateshwara University, Gajraula, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart transplantation and left ventricular assist devices (LVADs) have emerged as crucial interventions for end-stage heart failure, dramatically improving patient outcomes. This narrative review examines their historical context, indications, procedures, and outcomes, as well as their impact on long-term survival, quality of life, functional status, and mental health. While heart transplantation remains the optimal treatment, donor scarcity limits its application. LVADs have become a viable alternative, either as a bridge to transplantation or as destination therapy. Both interventions demonstrate similar long-term survival rates and significant improvements in health-related quality of life and functional status. However, they present distinct long-term management challenges, including immunosuppression needs for transplant recipients and device-related issues for LVAD patients. Mental health effects are considerable, necessitating psychological support and adaptive coping strategies. Complications such as infection, bleeding, and thrombosis remain concerns for both interventions. Patient selection criteria, technological advancements, and long-term management strategies are critical factors in optimizing outcomes. Future research should focus on device miniaturization, enhanced biocompatibility, and less invasive insertion techniques to further advance these therapies and improve patient care in end-stage heart failure.

Indexed as

end-stage heart failureheart transplantationleft ventricular assist deviceslong-term outcomesmental healthpatient selection

Identifiers

PMID39371854
PMCPMC11452842

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.