Evidence map›Paper›PMID 39372667›Full record

ReviewInternational journal of women's health2024

Unveiling the Network regulatory mechanism of ncRNAs on the Ferroptosis Pathway: Implications for Preeclampsia.

Yuan Zhang, Jingjing Zhang, Sirui Chen, Mianxin Li, Jin Yang, Jingsi Tan, Binsheng He, Lemei Zhu

Abstract readReview
In one paragraph

Review in International journal of women's health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuan Zhang *Hunan Key Laboratory of the Research and Development of Novel Pharmaceutical Preparations, Changsha 410219, People's Republic of China.ORCID 0009-0001-5177-1863
Jingjing Zhang *Department of Gynaecology and Obstetrics, Hunan Provincial Maternal and Child Health Hospital, Changsha 410219, People's Republic of China.
Sirui ChenHunan Key Laboratory of the Research and Development of Novel Pharmaceutical Preparations, Changsha 410219, People's Republic of China.
Mianxin LiHunan Key Laboratory of the Research and Development of Novel Pharmaceutical Preparations, Changsha 410219, People's Republic of China.ORCID 0009-0008-5231-1253
Jin YangHunan Key Laboratory of the Research and Development of Novel Pharmaceutical Preparations, Changsha 410219, People's Republic of China.
Jingsi TanHunan Key Laboratory of the Research and Development of Novel Pharmaceutical Preparations, Changsha 410219, People's Republic of China.
Binsheng He *Hunan Key Laboratory of the Research and Development of Novel Pharmaceutical Preparations, Changsha 410219, People's Republic of China.
Lemei Zhu *Hunan Key Laboratory of the Research and Development of Novel Pharmaceutical Preparations, Changsha 410219, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-coding RNAs (ncRNAs) are transcripts originating from the genome that do not serve as templates for protein synthesis. They function as epigenetic and translational regulators in various pathophysiological mechanisms, including cell proliferation and apoptosis. The ferroptosis signaling pathway, a novel mode of cell death, participates in numerous pathophysiological processes. Its signaling transmission is both complex and precise, featuring interconnected and interdependent pathways. Recent studies suggest that ncRNAs can finely regulate key genes in the ferroptosis pathway, thus modulating cellular functions, reducing oxidative stress, and maintaining maternal-fetal interface homeostasis. Future strategies targeting the ncRNA/ferroptosis axis may provide new perspectives and potential intervention points for treating preeclampsia. This article clarifies how the ncRNA/ferroptosis axis impacts preeclampsia, revealing how ncRNAs interact with ferroptosis, and pinpointing new molecular targets for the treatment of preeclampsia, thereby providing theoretical support for clinical strategies.

Indexed as

ferroptosisnetwork regulationnon-coding RNAspreeclampsiatreatment strategies

Identifiers

PMID39372667
PMCPMC11451465

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.