Evidence map›Paper›PMID 39373556›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2024

Enhancing Phototoxicity in BODIPY-Perylene Charge Transfer Dyads by Combined Iodination and Mesylation.

Rhianne C Curley, Ruben Arturo Arellano-Reyes, James N McPherson, Vickie McKee, Tia E Keyes

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Liposomal Delivery of Cell Impermeable Phototoxic Ru(II) Complexes.Chembiochem : a European journal of chemical biology · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rhianne C CurleySchool of Chemical Sciences, National Centre for Sensor Research, Dublin City University, Dublin, Ireland.
Ruben Arturo Arellano-ReyesSchool of Chemical Sciences, National Centre for Sensor Research, Dublin City University, Dublin, Ireland.
James N McPhersonDepartment of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, 5230, Odense M, Denmark.
Vickie McKeeDepartment of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, 5230, Odense M, Denmark.
Tia E KeyesSchool of Chemical Sciences, National Centre for Sensor Research, Dublin City University, Dublin, Ireland.ORCID https://orcid.org/0000-0002-4604-5533

Funding

Engineering and Physical Sciences Research Council EP/S023321HORIZON EUROPE Marie Sklodowska-Curie Actions 813920Science Foundation Ireland 19/FFP/6428 and 12/RC/2276_P2 and 18/EPSRC-CDT/3585
6 · The paper itself

Abstract

The uptake and phototoxicity of a family of BODIPY-perylene charge transfer dyads are compared in live cancer and non-cancer cell lines to evaluate their performance in imaging and photodynamic therapy (PDT). The impact of iodination and mesylation of the meso position of the compounds on their optical properties, cell uptake and toxicity are compared. Notably, across all derivatives the probes were minimally dark toxic up to 50 μM, (the maximum concentration tested), but exhibited outstanding phototoxicity with nanomolar IC

Indexed as

Boron CompoundsHalogenationPerylenePhotochemotherapyPhotosensitizing AgentsSinglet OxygenCell SurvivalFluorescent DyesHumansMCF-7 Cells4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneBoron CompoundsFluorescent DyesPerylenePhotosensitizing AgentsSinglet OxygenBODIPYIodinationPerylenePhotodynamic therapySpheroids

Identifiers

PMID39373556
PMCPMC11653243

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.