Evidence map›Paper›PMID 39373766›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

Effectiveness of an interactive online group intervention based on pain neuroscience education and graded exposure to movement in breast cancer survivors with chronic pain: a randomised controlled trial.

Patricia Martínez-Miranda, José Jesús Jiménez-Rejano, María Jesús Muñoz-Fernández, Cristina García-Muñoz, María Jesús Casuso-Holgado

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04965909 (Online Pain Neuroscience Education and Graded Exposure to Movement in Breast Cancer Survivors), which is not on this map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04965909 naunknown statusnot on this map

Online Pain Neuroscience Education and Graded Exposure to Movement in Breast Cancer Survivors: Protocol of a Randomised Controlled Trial.

TypeinterventionalSponsorUniversity of SevilleRan2021 to 2024Enrolled40ConditionsBreast Neoplasms, Pain, Chronic, Quality of LifeArmsOnline physiotherapy protocol based on pain neuroscience education and gradual exposure to movement.
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Review
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  11. Research trends on exercise and cancer pain relationships: a bibliometric analysis over the past three decades.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patricia Martínez-MirandaDepartamento de Ciencias de la Salud y Biomédicas, Universidad Loyola de Andalucía, Seville, Spain. patrimartinez37@gmail.com.ORCID http://orcid.org/0000-0001-8684-5829
José Jesús Jiménez-RejanoDepartment of Physiotherapy, Faculty of Nursing, Physiotherapy and Podiatry, Universidad de Sevilla, Seville, Spain. jjjimenez@us.es.ORCID http://orcid.org/0000-0003-3358-3305
María Jesús Muñoz-FernándezCTS 1110, UMSS Research Group, Andalusia, Seville, Spain. mariamufe_93@hotmail.com.ORCID http://orcid.org/0000-0001-9941-8818
Cristina García-MuñozDepartamento de Ciencias de la Salud y Biomédicas, Universidad Loyola de Andalucía, Seville, Spain. ccrissg@gmail.com.ORCID http://orcid.org/0000-0003-2621-2098
María Jesús Casuso-HolgadoCTS 1110, UMSS Research Group, Andalusia, Seville, Spain. mcasuso@us.es.ORCID http://orcid.org/0000-0002-4217-6827

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the effectiveness, compared with usual care, of an interactive online group programme combining pain neuroscience education (PNE) and graded exposure to movement (GEM) for improving quality of life and pain experience in breast cancer survivors with chronic pain.

methodsThis single-blind randomised controlled trial included a sample of 49 breast cancer survivors who were randomly assigned to two groups (experimental: n = 22 and control: n = 27). The experimental group received a 12-week person-centred online programme based on pain neuroscience education and therapeutic yoga as gradual exposure to movement, while the control group continued with their usual care. The primary outcome was quality of life (FACT-B + 4); the secondary outcomes were related to the experience of chronic pain (pain intensity, pain interference, catastrophizing, pain self-efficacy, kinesiophobia, and fear avoidance behaviours). All variables were assessed at four time points (T0, baseline; T1, after PNE sessions; T2, after yoga sessions; T3, at 3-month follow-up). For data analysis, ANOVA (2 × 4) analysis of variance (95% CI) was used when outcomes were normally distributed. If not, within-group and between-group comparisons were calculated.

resultsThirty-six participants were included in the analysis (control group, 22; experimental group, 14). A significant time * group effect was observed in favour of the experimental group regarding the global quality of life score (p = 0.010, η

conclusionsAn online intervention based on PNE and GEM appears to be more effective than usual care for improving quality of life in breast cancer survivors with chronic pain, as a time per group interaction was reported. In addition, the intervention also significantly improved the participants' experience of chronic pain. However, due to the study limitations further research is needed. Trial record: NCT04965909 (26/06/2021).

Indexed as

Breast NeoplasmsCancer SurvivorsChronic PainQuality of LifeAdultAgedCancer PainCatastrophizationFemaleHumansInternet-Based InterventionMiddle AgedNeurosciencesPain ManagementPatient Education as TopicSingle-Blind MethodBreast cancerGraded exposure to movementPain neuroscience educationQuality of lifeTherapeutic exerciseYoga

Identifiers

PMID39373766
PMCPMC11458701

What Socratic holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.