Evidence map›Paper›PMID 39374094›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2024

Absolute coronary flow and microvascular resistance before and after transcatheter aortic valve implantation.

Emanuele Gallinoro, Pasquale Paolisso, Dario Tino Bertolone, Giuseppe Esposito, Marta Belmonte, Attilio Leone, Michele Mattia Viscusi, Monika Shumkova, Cristina De Colle, Ivan Degrieck and 9 more

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Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Emanuele GallinoroCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Pasquale PaolissoCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Dario Tino BertoloneCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Giuseppe EspositoCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Marta BelmonteCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Attilio LeoneCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Michele Mattia ViscusiCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Monika ShumkovaCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Cristina De ColleCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Ivan DegrieckCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Filip CasselmanCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Martin PenickaCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Carlos ColletCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Jeroen SonckCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Eric WyffelsCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Jozef BartunekCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Bernard De BruyneCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Marc VanderheydenCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Emanuele BarbatoCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere aortic stenosis (AS) is associated with left ventricular (LV) remodelling, likely causing alterations in coronary blood flow and microvascular resistance.

aimsWe aimed to evaluate changes in absolute coronary flow and microvascular resistance in patients with AS undergoing transcatheter aortic valve implantation (TAVI).

methodsConsecutive patients with AS undergoing TAVI with non-obstructive coronary artery disease in the left anterior descending artery (LAD) were included. Absolute coronary flow (Q) and microvascular resistance (R

resultsIn 51 patients, Q and R were measured at rest and during hyperaemia before and after TAVI; in 20 (39%) patients, measurements were also obtained 6 months after TAVI. No changes occurred in resting and hyperaemic flow and resistance before and after TAVI nor after 6 months. However, at 6-month follow-up, a notable reverse LV remodelling resulted in a significant increase in hyperaemic perfusion (Q

conclusionsImmediately after TAVI, no changes occurred in absolute coronary flow or coronary flow reserve. Over time, the remodelling of the left ventricle is associated with increased hyperaemic perfusion.

Indexed as

Aortic Valve StenosisCoronary CirculationTranscatheter Aortic Valve ReplacementVascular ResistanceAgedAged, 80 and overAortic ValveCoronary Artery DiseaseCoronary VesselsEchocardiographyFemaleHumansMaleTreatment OutcomeVentricular Remodeling

Identifiers

PMID39374094
PMCPMC11443252

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.