Evidence map›Paper›PMID 39374162›Full record

ArticleJournal of applied clinical medical physics2024

Quantitative MRI biomarker for classification of clinically significant prostate cancer: Calibration for reproducibility across echo times.

Karoline Kallis, Christopher C Conlin, Courtney Ollison, Michael E Hahn, Rebecca Rakow-Penner, Anders M Dale, Tyler M Seibert

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Karoline KallisDepartment of Radiation Medicine and Applied Sciences, UC San Diego Health, La Jolla, California, USA.
Christopher C ConlinDepartment of Radiology, UC San Diego Health, La Jolla, California, USA.
Courtney OllisonDepartment of Radiation Medicine and Applied Sciences, UC San Diego Health, La Jolla, California, USA.
Michael E HahnDepartment of Radiology, UC San Diego Health, La Jolla, California, USA.
Rebecca Rakow-PennerDepartment of Radiology, UC San Diego Health, La Jolla, California, USA.
Anders M DaleDepartment of Radiology, UC San Diego Health, La Jolla, California, USA.
Tyler M SeibertDepartment of Radiation Medicine and Applied Sciences, UC San Diego Health, La Jolla, California, USA.

Funding

San Diego Clinical and Translational Research InstituteUL1TR000100 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S · 2012 to 2015
$19.7M
Improving assessment of prostate cancer bone metastases using advanced diffusion imagingK08EB026503 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SEIBERT, TYLER MICHAEL · 2019 to 2022
$805k
American Society for Radiation OncologyDepartment of Defense DOD/CDMRP PC220278NCATS NIH HHS UL1 TR000100NIBIB NIH HHS K08 EB026503NIH HHS NIH/NIBIB K08EB026503NIH HHS NIH UL1TR000100Prostate Cancer Foundation
6 · The paper itself

Abstract

purposeThe purpose of the present study is to develop a calibration method to account for differences in echo times (TE) and facilitate the use of restriction spectrum imaging restriction score (RSIrs) as a quantitative biomarker for the detection of clinically significant prostate cancer (csPCa).

methodsThis study included 197 consecutive patients who underwent MRI and biopsy examination; 97 were diagnosed with csPCa (grade group ≥ 2). RSI data were acquired three times during the same session: twice at minimum TE ~75 ms and once at TE = 90 ms (TEmin

resultsScaling factors for C

conclusionsThe proposed linear calibration method produces similar quantitative biomarker values for acquisitions with different TE, reducing TE-induced error by 72% and 55% for non-csPCa and csPCa, respectively.

Indexed as

Magnetic Resonance ImagingProstatic NeoplasmsAgedBiomarkers, TumorCalibrationHumansImage Processing, Computer-AssistedMaleMiddle AgedPrognosisReproducibility of ResultsBiomarkers, Tumorcalibrationdiffusion‐weighted imagingecho timeprostate cancerquantitative biomarkerrestricted spectrum imaging restriction score

Identifiers

PMID39374162
PMCPMC11539966

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.