Evidence map›Paper›PMID 39376995›Full record

ArticleInternational journal of surgical oncology2024

Novel Index Combining Pan-Immune-Inflammatory Index and Hemoglobin Levels (PIV/Hb) Predicts Trismus Rates Efficiently after Chemoradiotherapy in Locally Advanced Nasopharyngeal Cancer.

Efsun Somay, Busra Yilmaz, Erkan Topkan, Beyza Sirin Ozdemir, Duriye Ozturk, Ali Ayberk Besen, Huseyin Mertsoylu, Ugur Selek

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Efsun SomayDepartment of Oral and Maxillofacial Surgery Faculty of Dentistry Baskent University, Ankara, Türkiye.ORCID https://orcid.org/0000-0001-8251-6913
Busra YilmazDepartment of Oral and Maxillofacial Radiology School of Dental Medicine Bahcesehir University, Istanbul, Türkiye.ORCID https://orcid.org/0000-0003-0633-5648
Erkan TopkanDepartment of Radiation Oncology Faculty of Medicine Baskent University, Adana, Türkiye.ORCID https://orcid.org/0000-0001-8120-7123
Beyza Sirin OzdemirClinics of Radiation Oncology Medical Park Hospital, Antalya, Türkiye.ORCID https://orcid.org/0000-0001-9724-7875
Duriye OzturkDepartment of Radiation Oncology Faculty of Medicine Afyonkarahisar Health Sciences University, Afyonkarahisar, Türkiye.ORCID https://orcid.org/0000-0002-3265-2797
Ali Ayberk BesenClinics of Medical Oncology Adana Medical Park Hospital, Adana, Türkiye.ORCID https://orcid.org/0000-0002-7862-0192
Huseyin MertsoyluClinics of Medical Oncology Istinye University Adana Medical Park Hospital, Istanbul, Türkiye.ORCID https://orcid.org/0000-0002-1932-9784
Ugur SelekDepartment of Radiation Oncology School of Medicine Koc University, Istanbul, Türkiye.ORCID https://orcid.org/0000-0001-8087-3140

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the predictive potency of a novel index combining the pan-immune-inflammatory index and hemoglobin levels (PIV/Hb) for the prevalence of radiation-induced trismus (RIT) in patients with locally advanced nasopharyngeal cancer (LA-NPC) receiving concurrent chemoradiotherapy (CCRT). Methods: Data from 228 LA-NPC patients were retrospectively examined. Maximum mouth openings (MMO) were measured to confirm the presence of RIT, defined as MMOs ≤35 mm. Complete blood test results from the first day of CCRT were used to calculate PIV/Hb levels. A potential relationship between pretreatment PIV/Hb and the RIT status was evaluated using receiver operating characteristic (ROC) curve analysis. Results: Post-CCRT RIT was diagnosed in 20.2% of the patients. The ROC curve analysis determined 68.4 g/dL as the ideal PIV/Hb cutoff that effectively divided patients into two distinct groups (area under the curve: 94.7%; specificity: 86.4%; sensitivity: 87.4%). RIT was significantly more prevalent in the PIV/Hb > 68 group than in the PIV/Hb < 68 group (58.8% vs. 3.8%; Conclusion: Higher pretreatment levels of the novel PIV/Hb index predict increased RIT rates following definitive CCRT for LA-NPCs.

Indexed as

ChemoradiotherapyHemoglobinsNasopharyngeal NeoplasmsTrismusAdultAgedFemaleHumansInflammationMaleMiddle AgedNasopharyngeal CarcinomaPrognosisRetrospective StudiesROC CurveHemoglobins

Identifiers

PMID39376995
PMCPMC11458266

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.