Evidence map›Paper›PMID 39377203›Full record

ArticleJournal of the American Heart Association2024

α1

Victor A Flores-Tamez, Miguel Martín-Aragón Baudel, Junyoung Hong, Jade L Taylor, Lu Ren, Thanhmai Le, Arsalan U Syed, Yumna Moustafa, Navid Singhrao, Wendy R Lemus-Martinez and 15 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. CaThe Journal of physiology · 2026
    Article
  6. Review
  7. Amyloid β alters vascular CaThe Journal of physiology · 2025
    Article
  8. Article
  9. CaInflammation and regeneration · 2025
    Review
  10. CaInflammation and regeneration · 2024
    Review
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors.

Victor A Flores-TamezDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0001-8369-9192
Miguel Martín-Aragón BaudelDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0001-9399-4013
Junyoung HongDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0002-7261-2204
Jade L TaylorDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0001-7158-2712
Lu RenDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0002-9731-8562
Thanhmai LeDepartment of Pharmacology University of California Davis Davis CA USA.
Arsalan U SyedDepartment of Pharmacology University of California Davis Davis CA USA.
Yumna MoustafaDepartment of Pharmacology University of California Davis Davis CA USA.
Navid SinghraoDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0001-7438-2409
Wendy R Lemus-MartinezDepartment of Pharmacology University of California Davis Davis CA USA.
Gopireddy R ReddyDepartment of Pharmacology University of California Davis Davis CA USA.
Victoria RamerDepartment of Pharmacology University of California Davis Davis CA USA.
Kwun Nok Mimi ManDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0002-0132-9129
Peter BartelsDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0001-5852-1835
Ye Chen-IzuDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0003-4818-9570
Chao-Yin ChenDepartment of Pharmacology University of California Davis Davis CA USA.
Sergi SimoDepartment of Cell Biology & Human Anatomy University of California Davis Davis CA USA.ORCID 0000-0002-8344-0313
Eamonn J DicksonDepartment of Physiology & Membrane Biology University of California Davis Davis CA USA.ORCID 0000-0001-8619-7630
Stefano MorottiDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0001-8679-665X
Eleonora GrandiDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0002-4401-8857
L Fernando SantanaDepartment of Physiology & Membrane Biology University of California Davis Davis CA USA.ORCID 0000-0002-4297-8029
Johannes W HellDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0001-7960-7531
Mary C HorneDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0002-2799-3212
Madeline Nieves-CintrónDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0003-1935-8400
Manuel F NavedoDepartment of Pharmacology University of California Davis Davis CA USA.ORCID 0000-0001-6864-6594

Funding

Coupling of Vascular Cav1.2 Channels In Health & DiseaseR01HL121059 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI NAVEDO, MANUEL F · 2015 to 2024
$4.5M
Role of a-actinin in Cav1.2 FunctionR01AG055357 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JOHANNES W HELL · 2016 to 2026
$4.0M
Cerebral Vascular Smooth Muscle Dysfunction in Alzheimer's DiseaseR01HL149127 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI NAVEDO, MANUEL F · 2019 to 2022
$2.7M
cAMP signaling in vascular smooth muscle in health and diseaseR01HL161872 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI NAVEDO, MANUEL F · 2022 to 2025
$2.6M
Postsynaptic Signaling by Norepinephrine and cAMPR01NS123050 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JOHANNES W HELL · 2022 to 2026
$2.3M
Mechanisms of VSM dysfunction in diabetes and HFpEFR01HL171014 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Manuel F Navedo, Madeline Nieves-Cintron · 2024 to 2026
$2.0M
Modeling of subcellular signaling crosstalk in failing myocytesR00HL138160 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MOROTTI, STEFANO · 2020 to 2022
$722k
NHLBI NIH HHS R00 HL138160NHLBI NIH HHS R01 HL121059NHLBI NIH HHS R01 HL149127NHLBI NIH HHS R01 HL161872NHLBI NIH HHS R01 HL171014NIA NIH HHS R01 AG055357NINDS NIH HHS R01 NS123050
6 · The paper itself

Abstract

backgroundIncreased vascular Ca METHODS AND

resultsThe hypothesis was examined in freshly isolated mesenteric arteries and arterial myocytes from control and angiotensin II-infused mice. Specific techniques include superresolution imaging, proximity ligation assay, patch-clamp electrophysiology, Ca

conclusionsResults suggest an essential role for α1

Indexed as

Angiotensin IICalcium Channels, L-TypeHypertensionMesenteric ArteriesAnimalsBlood PressureCalcium SignalingDisease Models, AnimalMaleMiceMice, Inbred C57BLMuscle, Smooth, VascularMyocytes, Smooth MusclePhosphorylationVasoconstrictionAngiotensin IICACNA1C protein, mouseCalcium Channels, L-Typecardiovascularclusteringcooperativitydiabeteshypertension

Identifiers

PMID39377203
PMCPMC11935578

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.