Evidence map›Paper›PMID 39377959›Full record

Trial reportBiological trace element research2025

Comparison of the Effect of Omega-3 vs. MCT Supplementation on Iron-Related Indices in Patients Undergoing Dialysis.

Farkhondeh Alami, Seyedeh Hayedeh Mousavi Shalmani, Zahra Mahmoudi, Narjes Nooriani, Zahra Mousavi, Arezoo Amjadi, Mohammad Masoumvand, Malikeh Mohajerani, Khadijeh Abbasi Mobarakeh, Asma Rajabi Harsini and 5 more

Abstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Biological trace element research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Farkhondeh AlamiStudent Research Committee, Department of Nutrition, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Seyedeh Hayedeh Mousavi ShalmaniSchool of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Zahra MahmoudiDepartment of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Narjes NoorianiDepartment of Community Nutrition, School of Nutrition and Food Sciences, Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Zahra MousaviNursing and Midwifery school, Shahed University, Tehran, Iran.
Arezoo AmjadiDepartment of Nutrition, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Mohammad MasoumvandStudent Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Malikeh MohajeraniDepartment of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Khadijeh Abbasi MobarakehDepartment of Community Nutrition, School of Nutrition and Food Sciences, Nutrition and Food Security Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Asma Rajabi HarsiniDepartment of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Hanieh ShafaeiMaster's Student in Pediatric Nursing, Shahid Beheshti College of Midwifery, Guilan University of Medical Sciences, Rasht, Iran.
Saeed OmidiSchool of Health, Guilan University of Medical Sciences, Rasht, Iran.
Sara KhoshdoozFaculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Saeid DoaeiDepartment of Community Nutrition, Faculty of Nutrition Sciences and Food Technology, School of Nutrition and Food Sciences, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran. sdoaee@yahoo.com.
Masoud KhosraviUrology Research Center, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran. drmasoudkhosravi@gmail.com.

Funding

Guilan University of Medical Sciences 74859
6 · The paper itself

Abstract

Chronic kidney disease (CKD), characterized by progressive kidney failure, significantly increases mortality and comorbidity risks such as anemia. This study contrasts the impacts of omega-3 and medium-chain triglycerides (MCT) oil on levels of iron, ferritin, total iron-binding capacity (TIBC), hemoglobin (Hb), and transferrin saturation in patients with CKD undergoing dialysis. This interventional trial was conducted on 120 patients with CKD undergoing dialysis in Rasht, Iran. For 8 weeks, the omega-3 group was orally administered three 1000-mg capsules of omega-3 fatty acid supplement, and the MCT group was administered three 1000-mg capsules containing MCT oil daily. Serum concentrations of ferritin, iron, TIBC, Hb, and transferrin saturation were assessed pre-intervention and after the intervention. There was a significant increase in serum iron levels in the MCT group compared to the omega-3 group (103.72 ± 57.8 vs. 77.48±40.13; P = 0.031). No effect was found regarding other iron-related factors such as TIBC, Hb, transferrin saturation, and ferritin levels. The results of our study indicated that taking MCT oil increased serum iron levels compared to omega-3 supplementation in patients with CKD undergoing dialysis. Further research is needed to better understand the potential benefits of MCT oils in patients with CKD.

Indexed as

Dietary SupplementsFatty Acids, Omega-3IronRenal DialysisRenal Insufficiency, ChronicTriglyceridesAdultAgedFemaleFerritinsHemoglobinsHumansMaleMiddle AgedTransferrinFatty Acids, Omega-3FerritinsHemoglobinsIronTransferrinTriglyceridesChronic kidney diseaseDialysisFerritinIronMCT oilOmega-3 fatty acid

Identifiers

PMID39377959

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.