Evidence map›Paper›PMID 39379177›Full record

ReviewInternational wound journal2024

Modulations of the skin microbiome in skin disorders: A narrative review from a wound care perspective.

Antonia Piazzesi, Matteo Scanu, Guido Ciprandi, Lorenza Putignani

Abstract readReview
In one paragraph

Review in International wound journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Observational
  6. Review
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Antonia PiazzesiImmunology, Rheumatology and Infectious Diseases Research Unit, Unit of the Microbiome, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.ORCID https://orcid.org/0000-0002-7591-6473
Matteo ScanuImmunology, Rheumatology and Infectious Diseases Research Unit, Unit of the Microbiome, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Guido CiprandiResearch Institute Division of Plastic and Maxillofacial Surgery, Department of Surgery, Bambino Gesu' Children's Hospital, IRCCS, Rome, Italy.
Lorenza PutignaniUnit of Microbiology and Diagnostic Immunology, Unit of Microbiomics; and Immunology, Rheumatology and Infectious Diseases Research Unit, Unit of the Microbiome, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

Funding

Ministero della Salute, Current Research Funds
6 · The paper itself

Abstract

The cutaneous microbiome represents a highly dynamic community of bacteria, fungi and viruses. Scientific evidence, particularly from the last two decades, has revealed that these organisms are far from being inconsequential microscopic hitchhikers on the human body, nor are they all opportunistic pathogens waiting for the chance to penetrate the skin barrier and cause infection. In this review, we will describe how dermatological diseases have been found to be associated with disruptions and imbalances in the skin microbiome and how this new evidence had shaped the diagnosis and clinical practice relating to these disorders. We will identify the microbial agents which have been found to directly exacerbate skin diseases, as well as those which can ameliorate many of the symptoms associated with dermatological disorders. Furthermore, we will discuss the studies which suggest that bacteriotherapy, either by topical use of probiotics or by bacteria-derived compounds, can rectify skin microbial imbalances, thereby offering a promising alternative to antibiotic treatment and reducing the risks of antibiotic resistance.

Indexed as

MicrobiotaSkinSkin DiseasesAnti-Bacterial AgentsFemaleHumansMaleProbioticsWound HealingAnti-Bacterial Agentsmicrobiotamultiple drug resistanceprobioticsskinwounds and injuries

Identifiers

PMID39379177
PMCPMC11461044

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.