Evidence map›Paper›PMID 39380183›Full record

ArticleChemMedChem2024

A Dual Action Platinum(IV) Complex with Self-assembly Property Inhibits Prostate Cancer through Mitochondrial Stress Pathway.

Muhammad Nafees, Muhammad Hanif, Raja Muhammad Asif Khan, Faisal Faiz, Piaoping Yang

Abstract read
In one paragraph

Article in ChemMedChem, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammad NafeesKey Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P.R. China.ORCID 0000-0001-8594-4243
Muhammad HanifSchool of Chemical Sciences, University of Auckland, Private Bag 92019, Auckland, 1142, New Zealand.ORCID 0000-0002-2256-2317
Raja Muhammad Asif KhanDepartment of Chemistry, School of Natural Sciences, National University of Sciences and Technology (NUST) H-12, Islamabad, 44000, Pakistan.ORCID 0009-0008-5100-1296
Faisal FaizSchool of Electronics and Information Engineering, Shenzhen University, Shenzhen, 518060, P.R. China.ORCID 0000-0001-8243-0255
Piaoping YangKey Laboratory of Superlight Materials and Surface Technology, Ministry of Education, College of Materials Science and Chemical Engineering, Harbin Engineering University, Harbin, 150001, P.R. China.ORCID 0000-0002-9555-1803

Funding

Fundamental Research Funds for the Central Universities and the National Natural Science Foundation of China U22 A20347
6 · The paper itself

Abstract

Platinum(IV) prodrugs are highly promising anticancer agents because they can selectively target tumors and minimize the adverse effects associated with their Pt

Indexed as

Antineoplastic AgentsApoptosisCell ProliferationDrug Screening Assays, AntitumorMitochondriaProstatic NeoplasmsCell Line, TumorCoordination ComplexesDose-Response Relationship, DrugHumansMaleMembrane Potential, MitochondrialMolecular StructureOrganoplatinum CompoundsReactive Oxygen SpeciesStructure-Activity RelationshipAntineoplastic AgentsCoordination ComplexesOrganoplatinum CompoundsReactive Oxygen SpeciesAnticancer agentsEnergy disruptionMetal-based drugsMitochondrial damageProstate cancerPtIV complexesSelf-assembly

Identifiers

PMID39380183
PMCPMC11581420

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.