Evidence mapPaperPMID 39382013Full record

ReviewFuture cardiology2024

Linking hearts and minds: understanding the cardiovascular impact of bipolar disorder.

Darshini Shah, Bhupinder Singh, Fnu Varnika, Fremita Chelsea Fredrick, Anish Kumar Reddy Meda, Kanishk Aggarwal, Rohit Jain

Abstract readReview
In one paragraph

Review in Future cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Darshini ShahDepartment of Psychiatry, GCS Medical College, Hospital and Research Centre, Gujarat, 380025, India.ORCID 0009-0003-2175-2877
Bhupinder SinghDepartment of Medicine, Icahn School of Medicine at Mount Sinai, NYC Health + Hospitals, Queens,New York, NY 11432, USA.ORCID 0009-0004-9218-0885
Fnu VarnikaDepartment of Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, 133207, India.ORCID 0009-0004-9620-5314
Fremita Chelsea FredrickDepartment of Medicine, Avalon University School of Medicine, Willemstad, Curacao.ORCID 0009-0002-3341-7251
Anish Kumar Reddy MedaDepartment of Medicine, Avalon University School of Medicine, Willemstad, Curacao.ORCID 0009-0008-2008-5992
Kanishk AggarwalDayanand Medical College and Hospital, Ludhiana, 141001, India.ORCID 0009-0005-7518-446X
Rohit JainPenn State Health Milton S. Hershey Medical Center, Hershey, PA 17033, USA.ORCID 0000-0002-9101-2351

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bipolar disorder is a severe and recurring condition that has become a significant public health issue globally. Studies indicate a heightened risk and earlier onset of cardiovascular diseases among individuals with bipolar disorder, potentially increasing mortality rates. The chronic nature of bipolar disorder leads to disturbances across multiple systems, including autonomic dysfunction, over-activation of the hypothalamic-pituitary-adrenal axis and increased levels of peripheral inflammatory markers. These disruptions cause endothelial damage, the formation of plaques and blood clots, in addition to the medications used to treat bipolar disorder and genetic associations contributing to cardiovascular disease development. Understanding the complex interplay between bipolar disorder and cardiovascular events is essential for the prevention and effective management of cardiovascular conditions in individuals with bipolar disorder.

Indexed as

Bipolar DisorderCardiovascular DiseasesHumansHypothalamo-Hypophyseal SystemPituitary-Adrenal SystemRisk Factorsbipolar disordercardiovascular disorderheart brain axissmokingtypical antipsychotics

Identifiers

PMID39382013
PMCPMC11552481

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.