Evidence map›Paper›PMID 39382016›Full record

ArticlePharmacogenomics2024

Analysis of the current situation of pharmacogenomics in terms of educational and healthcare needs in Egypt and Lebanon.

Sahar M El-Gowilly, Heba A Metwaly, Dalia Makhlouf, Nehal Elmansoury, Salwa A Abuiessa, Amani A Sorour, Mohamed Hussein Abdelgalil, Mirna Fawaz, Asmaa M Abushady, Mariam Gamaleldin and 15 more

Abstract read
In one paragraph

Article in Pharmacogenomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Sahar M El-GowillyDepartment of Pharmacology & Toxicology, Faculty of Pharmacy, Alexandria University, Alexandria, 21500, Egypt.ORCID 0000-0002-7469-1647
Heba A MetwalyDepartment of Biochemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21500, Egypt.ORCID 0000-0002-9593-4687
Dalia MakhloufDepartment of Pharmaceutical Services, Children's Cancer Hospital Egypt 57357, Cairo, Egypt.ORCID 0009-0003-7880-544X
Nehal ElmansouryDepartment of Biochemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21500, Egypt.
Salwa A AbuiessaDepartment of Pharmacology & Toxicology, Faculty of Pharmacy, Alexandria University, Alexandria, 21500, Egypt.ORCID 0000-0002-0269-534X
Amani A SorourDepartment of Biochemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21500, Egypt.ORCID 0000-0002-1498-5598
Mohamed Hussein AbdelgalilDepartment of Biochemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21500, Egypt.ORCID 0009-0009-7377-0608
Mirna FawazDepartment of Medical Laboratory Technology, Faculty of Health Sciences, Beirut Arab University, Beirut 11-5020, Lebanon.
Asmaa M AbushadySchool of Biotechnology, Nile University, Giza, Egypt.
Mariam GamaleldinSchool of Biotechnology, Nile University, Giza, Egypt.ORCID 0000-0001-6281-7102
Tarek M AbdelghanyDepartment of Pharmacology & Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt.
Rajaa FakhouryDepartment of Medical Laboratory Technology, Faculty of Health Sciences, Beirut Arab University, Beirut 11-5020, Lebanon.
Rasha AbdelhadyPharmacology & Toxicology Department, Faculty of Pharmacy, Fayoum University, Fayoum, 63514, Egypt.ORCID 0000-0003-1963-8525
Amal Mh GhanimBiochemistry department, Faculty of Pharmacy, Fayoum University, Fayoum, 63514, Egypt.ORCID 0000-0001-7666-6683
Samah ShehataBiochemistry department, Faculty of Pharmacy, Fayoum University, Fayoum, 63514, Egypt.ORCID 0000-0001-9515-6283
Marwa KamalClinical pharmacy department, Faculty of Pharmacy, Fayoum University, Fayoum, 63514, Egypt.ORCID 0000-0002-3261-0327
Rehab BahyMicrobiology & Immunology Department, Faculty of Pharmacy, Fayoum University, Fayoum, 63514, Egypt.ORCID 0000-0002-2868-928X
Sanaa A HaroonPlant protection department, Faculty of Agriculture, Fayoum University, Fayoum, 63514, Egypt.ORCID 0000-0002-4414-8416
Vangelis G ManolopoulosLaboratory of Pharmacology, Medical School, Democritus University of Thrace, Dragana Campus, 68100, Alexandroupolis, Greece.ORCID 0000-0003-0849-5469
Ingolf CascorbiInstitute of Experimental & Clinical Pharmacology, University Hospital Schleswig-Holstein, Campus Kiel, Germany.ORCID 0000-0002-2182-9534
Ann DalyTranslational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.ORCID 0000-0002-7321-0629
Noha F AbdelkaderDepartment of Pharmacology & Toxicology, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, 11562, Egypt.ORCID 0000-0001-7026-283X
Said El ShamiehDepartment of Medical Laboratory Technology, Faculty of Health Sciences, Beirut Arab University, Beirut 11-5020, Lebanon.ORCID 0000-0002-8522-0445
Mohamed NagyDepartment of Pharmaceutical Services, Children's Cancer Hospital Egypt 57357, Cairo, Egypt.ORCID 0000-0001-9807-788X
Ahmed WahidDepartment of Biochemistry, Faculty of Pharmacy, Alexandria University, Alexandria, 21500, Egypt.ORCID 0000-0003-3613-2796

Funding

Erasmus+ 617303-EPP-1-2020-1-EG-EPPKA2-CBHE-JP
6 · The paper itself

Abstract

Pharmacogenomics (PGx) is a practice that investigates the link between genetic differences and drug response in patients. This can improve treatment effectiveness and reduce harmful side effects. However, has yet to be adequately realized in developing nations. Three surveys were conducted between November 2022 to March 2023 in Egypt and Lebanon. The first survey assessed availability of PGx testing in different healthcare facilities; the second one assessed knowledge, interest and attitude toward learning about PGx among pharmacists and physicians; and the third one assessed interest in providing PGx education at academic levels. In Egypt, a few of the surveyed healthcare facilities are conducting some form of pharmacogenetic testing. In Lebanon, very few germline pharmacogenomic tests are offered in Greater Beirut's leading hospitals, and no other testing was recorded. PGx education attracts considerable interest, with 34.3% of pharmacists very interested and 48.8% interested. Similarly, 24.8% of total physicians were very interested while 44.8% were interested. Academic professionals in the surveyed institutions in both countries agreed on the need for educational programs in PGx and 78.2% agreed that there were good opportunities for implementing PGx testing. These findings clearly indicate the need to develop and implement educational programs in PGx in the Middle-East.

Indexed as

PharmacogeneticsEgyptFemaleHealth Knowledge, Attitudes, PracticeHealth Services Needs and DemandHumansLebanonMalePharmacistsPharmacogenomic TestingPhysiciansSurveys and Questionnairesegypthealthcare educationlebanonpharmacogeneticspharmacogenomics

Identifiers

PMID39382016
PMCPMC11492645

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.