Evidence map›Paper›PMID 39382939›Full record

ReviewDevelopment (Cambridge, England)2024

Advancing stem cell technologies for conservation of wildlife biodiversity.

Ashlee M Hutchinson, Ruth Appeltant, Tom Burdon, Qiuye Bao, Rhishikesh Bargaje, Andrea Bodnar, Stuart Chambers, Pierre Comizzoli, Laura Cook, Yoshinori Endo and 31 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Development (Cambridge, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Biobanking biodiversity: recent strategies, challenges, and opportunities.The Journal of reproduction and development · 2026
    Review
  10. Review
  11. Advancing Wildlife Conservation Through Biobanking in South America.Animals : an open access journal from MDPI · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Can stem cells save the animals?Nature methods · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

41 authors.

Ashlee M HutchinsonRevive & Restore, 1505 Bridgeway, Suite 203, Sausalito, CA 94965, USA.
Ruth AppeltantGamete Research Centre, Veterinary Physiology and Biochemistry, Department of Veterinary Sciences, University of Antwerp, 2610 Wilrijk, Belgium.
Tom BurdonThe Roslin Institute, RDSVS, University of Edinburgh, Easter Bush Campus, Midlothian EH25 9RG, UK.
Qiuye BaoIMCB-ESCAR, A*STAR, 61 Biopolis Drive, Proteos, 138673Singapore.
Rhishikesh BargajeConception Bioscience, Berkeley, CA 94710, USA.
Andrea BodnarGloucester Marine Genomics Institute, 417 Main St, Gloucester, MA 01930, USA.
Stuart ChambersBrightfield Therapeutics, South San Francisco, CA 94080, USA.
Pierre ComizzoliSmithsonian National Zoo and Conservation Biology Institute, 3001 Connecticut Ave., NW Washington, DC 20008, USA.
Laura CookLawrence Berkeley National Laboratory, 1 Cyclotron Rd, Berkeley, CA 94720, USA.ORCID 0000-0002-4459-2592
Yoshinori EndoUniversity of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093, USA.
Bob HarmanVet-Stem Inc. & Personalized Stem Cells, Inc., 14261 Danielson Street, Poway, CA 92064, USA.
Katsuhiko HayashiOsaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
Thomas HildebrandtLeibniz Institute for Zoo and Wildlife Research, Alfred-Kowalke-Straße 17, 10315 Berlin, Germany.
Marisa L KorodySan Diego Zoo Wildlife Alliance, 2920 Zoo Dr, San Diego, CA 92101, USA.
Uma LakshmipathyThermo Fisher Scientific, 168 Third Avenue, Waltham, MA 02451, USA.
Jeanne F LoringThe Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA.
Clara MungerDepartment of Biochemistry, University of Cambridge, Hopkins Building, Downing Site, Tennis Court Road, Cambridge CB2 1QW, UK.
Alex H M NgGC Therapeutics, 610 Main St., North Cambridge, MA 02139, USA.
Ben NovakRevive & Restore, 1505 Bridgeway, Suite 203, Sausalito, CA 94965, USA.
Manabu OnumaNational Institute for Environmental Studies, 16-2 Onogawa, City of Tsukuba, Ibaraki 305-8506, Japan.
Sara OrdColossal Biosciences, 1401 Lavaca St, Unit #155 Austin, TX 78701, USA.
Monique ParisIBREAM (Institute for Breeding Rare and Endangered African Mammals), Edinburgh EH3 6AT, UK.
Andrew J PaskUniversity of Melbourne, Parkville, VIC 3052, Australia.ORCID 0000-0002-1900-2263
Francisco PelegriUniversity of Wisconsin-Madison, 500 Lincoln Dr, Madison, WI 53706, USA.
Martin PeraJackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Ryan PhelanRevive & Restore, 1505 Bridgeway, Suite 203, Sausalito, CA 94965, USA.
Benyamin RosentalThe Shraga Segal Department of Microbiology, Immunology, and Genetics, Faculty of Health Sciences, Center for Regenerative Medicine and Stem Cells, Ben Gurion University of the Negev, Beer Sheva 8410501, Israel.
Oliver A RyderSan Diego Zoo Wildlife Alliance, 2920 Zoo Dr, San Diego, CA 92101, USA.
Woranop SukparangsiDepartment of Biology, Faculty of Science, Burapha University, 169 Long-Had Bangsaen Rd, Saen Suk, Chon Buri District, Chon Buri 20131, Thailand.
Gareth SullivanDepartment of Pediatric Research, Oslo University Hospital, P.O. Box 4950 Nydalen, N-0424 Oslo, Norway.
Nicole Liling TayIMCB-ESCAR, A*STAR, 61 Biopolis Drive, Proteos, 138673Singapore.
Nikki Traylor-KnowlesRosenstiel School of Marine, Atmospheric, and Earth Science, University of Miami,4600, Rickenbacker Cswy, Key Biscayne, FL 33149, USA.
Shawn WalkerViaGen Pets & Equine, PO Box 1119, Cedar Park, TX 78613, USA.
Antonia WeberlingAll Souls College, University of Oxford, Oxford OX1 4AL, UK.
Deanne J WhitworthUniversity of Queensland, Sir Fred Schonell Drive, Brisbane, Queensland, 4072, Australia.
Suzannah A WilliamsUniversity of Oxford, Oxford OX1 2JD, UK.
Jessye WojtusikOmaha's Henry Doorly Zoo & Aquarium, 3701 S 10th St, Omaha, NE 68107, USA.
Jun WuUniversity of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.
Qi-Long YingKeck School of Medicine of University of Southern California, 1975 Zonal Ave, Los Angeles, CA 90033, USA.
Thomas P ZwakaDepartment of Cell, Developmental, and Regenerative Biology, and Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Timo N KohlerDepartment of Biochemistry, University of Cambridge, Hopkins Building, Downing Site, Tennis Court Road, Cambridge CB2 1QW, UK.ORCID 0000-0003-1949-0655

Funding

University of Cambridge
6 · The paper itself

Abstract

Wildlife biodiversity is essential for healthy, resilient and sustainable ecosystems. For biologists, this diversity also represents a treasure trove of genetic, molecular and developmental mechanisms that deepen our understanding of the origins and rules of life. However, the rapid decline in biodiversity reported recently foreshadows a potentially catastrophic collapse of many important ecosystems and the associated irreversible loss of many forms of life on our planet. Immediate action by conservationists of all stripes is required to avert this disaster. In this Spotlight, we draw together insights and proposals discussed at a recent workshop hosted by Revive & Restore, which gathered experts to discuss how stem cell technologies can support traditional conservation techniques and help protect animal biodiversity. We discuss reprogramming, in vitro gametogenesis, disease modelling and embryo modelling, and we highlight the prospects for leveraging stem cell technologies beyond mammalian species.

Indexed as

Animals, WildBiodiversityConservation of Natural ResourcesStem Cell ResearchAnimalsStem CellsBiodiversityConservationDisease modellingIn vitro gametogenesisIPSCStem cells

Identifiers

PMID39382939
PMCPMC11491813

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.