Evidence map›Paper›PMID 39384892›Full record

ArticleScientific reports2024

Biochemical rationale for transfusion of high titre COVID-19 convalescent plasma.

Caro Verbrugghe, Elise Wouters, Rosalie Devloo, Visa Nurmi, Sabrina Seghers, Dominique De Bleser, Heli Harvala, Veerle Compernolle, Hendrik B Feys

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Caro VerbruggheTransfusion Research Center, Belgian Red Cross-Flanders, Ghent, Belgium.
Elise WoutersTransfusion Research Center, Belgian Red Cross-Flanders, Ghent, Belgium.
Rosalie DevlooTransfusion Research Center, Belgian Red Cross-Flanders, Ghent, Belgium.
Visa NurmiNuffield Department of Medicine, University of Oxford, Oxford, UK.
Sabrina SeghersTransfusion Innovation Center, Belgian Red Cross-Flanders, Ghent, Belgium.
Dominique De BleserTransfusion Innovation Center, Belgian Red Cross-Flanders, Ghent, Belgium.
Heli HarvalaRadcliffe Department of Medicine, University of Oxford, Oxford, UK.
Veerle CompernolleTransfusion Research Center, Belgian Red Cross-Flanders, Ghent, Belgium.
Hendrik B FeysTransfusion Research Center, Belgian Red Cross-Flanders, Ghent, Belgium. hendrik.feys@rodekruis.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to model binding of donor antibodies to virus that infects COVID-19 patients following transfusion of convalescent plasma (CCP). An immunosorbent assay was developed to determine apparent affinity (K

Indexed as

Antibodies, ViralCOVID-19COVID-19 SerotherapyImmunization, PassiveImmunoglobulin GSARS-CoV-2AdultBlood DonorsFemaleHumansImmunoglobulin AMaleMiddle AgedViral LoadAntibodies, ViralImmunoglobulin AImmunoglobulin GAffinityConvalescent plasmaCOVID-19SARS-CoV-2Transfusion

Identifiers

PMID39384892
PMCPMC11464705

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.