Evidence map›Paper›PMID 39385258›Full record

Trial reportCardiovascular diabetology2024

The relationship between repeated measurements of HbA

A S Carew, R A Warren, M P Bancks, M A Espeland, J L Bahnson, C L Lewis, A P Levy, J L Sapp, R Urquhart, J L Wang and 2 more

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Cardiovascular diabetology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Relationship between time-varying achieved HbABMJ open diabetes research & care · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

A S CarewQEII Health Sciences Centre, Nova Scotia Health, Halifax, Canada.
R A WarrenQEII Health Sciences Centre, Nova Scotia Health, Halifax, Canada.
M P BancksDepartment of Epidemiology and Prevention, Wake Forest University School of Medicine, Winston-Salem, USA.
M A EspelandDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, USA.
J L BahnsonDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, USA.
C L LewisDepartment of Epidemiology, University of Alabama Birmingham, Birmingham, USA.
A P LevyRappaport Faculty of Medicine, Technion Israel Institute of Technology, Haifa, Israel.
J L SappQEII Health Sciences Centre, Nova Scotia Health, Halifax, Canada.
R UrquhartQEII Health Sciences Centre, Nova Scotia Health, Halifax, Canada.
J L WangDepartment of Community Health and Epidemiology, Dalhousie University, Halifax, Canada.
E B RimmDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, USA.
L E CahillQEII Health Sciences Centre, Nova Scotia Health, Halifax, Canada. leah.cahill@dal.ca.

Funding

HEALTH OUTCOMES OF WEIGHT-LOSS: DATA COORDINATING CENTERU01DK057136 · WAKE FOREST UNIVERSITY HEALTH SCIENCES · 1999 to 2005
$18.5M
CIHR Doctoral AwardCIHR PJT173471Government of Nova Scotia Graduate ScholarshipHeart and Stroke Foundation of Canada Bright Red Mission AwardKillam Trusts Doctoral AwardNIDDK NIH HHS U01 DK057136NIH HHS DK057136
6 · The paper itself

Abstract

backgroundIn the ACCORD study, participants with the haptoglobin (Hp) 2-2 phenotype and glycated hemoglobin (HbA

objectiveTo investigate how reaching clinically relevant HbA

methodsCox regression models with time-varying covariables were used to quantify the association between time-varying achieved HbA

resultsCompared with HbA

conclusionThe differences in our results compared to our previous findings may be due to variations in the study populations and factors associated with weight loss, making it difficult to draw definitive conclusions. Our current findings should be considered in the context of hypothesis generation, and ideally, will encourage additional research in this field.

Indexed as

BiomarkersCoronary Artery DiseaseDiabetes Mellitus, Type 2Glycated HemoglobinHaptoglobinsPhenotypeAgedBlood GlucoseFemaleGlycemic ControlHumansHypoglycemic AgentsIncidenceMaleMiddle AgedProspective StudiesBiomarkersBlood GlucoseGlycated HemoglobinHaptoglobinshemoglobin A1c protein, humanHP protein, humanHypoglycemic AgentsCoronary artery diseaseEpidemiologyGenetic associationGlycated hemoglobinHaptoglobin phenotypeType 2 diabetes mellitus

Identifiers

PMID39385258
PMCPMC11466022

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.