Evidence map›Paper›PMID 39386185›Full record

ArticleBioMedicine2024

Effect of inulin from dahlia tubers (

Ismawati, Saryono, Mukhyarjon, Ilhami Romus, Veni D Putri, Sri Yanti, Fitri Dyna, Nada I Adesti

Abstract read
In one paragraph

Article in BioMedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Inulin andFrontiers in endocrinology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

IsmawatiFaculty of Medicine, Universitas Riau, Pekanbaru, Indonesia.
SaryonoChemistry Study Program, Faculty of Mathematics and Natural Sciences, Universitas Riau, Pekanbaru, Indonesia.
MukhyarjonFaculty of Medicine, Universitas Riau, Pekanbaru, Indonesia.
Ilhami RomusFaculty of Medicine, Universitas Riau, Pekanbaru, Indonesia.
Veni D PutriNursing Study Program, STIKes Payung Negeri Pekanbaru, Pekanbaru, Indonesia.
Sri YantiNursing Profession Study Program, STIKes Payung Negeri Pekanbaru, Pekanbaru, Indonesia.
Fitri DynaNursing Profession Study Program, STIKes Payung Negeri Pekanbaru, Pekanbaru, Indonesia.
Nada I AdestiMedical Doctor Study Program, Faculty of Medicine, Riau University, Pekanbaru, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dahlia ( Methods: In this experimental study, 20 male Wistar rats were randomly allocated to five groups. Group I served as the control, Group II as the STZ-induced diabetic group, Group III as the STZ-induced diabetic group treated with inulin (0.5 g/kgBW), Group IV as the STZ induced diabetic group treated with inulin (1.0 g/kgBW), and Group V as the STZ-induced diabetic group treated with inulin (1.5 g/kgBW). The inulin was administered for 21 days. The degree of insulitis was evaluated using a scoring system, serum insulin concentration via ELISA, and insulin expression in the pancreas through immunohistochemistry. Results: Administration of inulin from dahlia tubers significantly reduced serum glucose concentrations in diabetic rats. Notably, only inulin extracts at doses of 1 g/kgBW and 1.5 g/kgBW showed a significant reduction in insulitis and HOMA-IR index in diabetic rats, while the 0.5 g/kgBW inulin extract reduced insulitis without affecting HOMA-IR. Inulin extract administration did not affect insulin expression in serum or pancreatic tissue. Conclusions: Inulin from dahlia tuber can exert antidiabetic properties by improving insulin resistance and insulitis. These studies suggest the great potential of dahlia tubers as the source of inulin for prebiotic functional foods.

Indexed as

Dahlia tubersDiabetes mellitusInsulinInulin

Identifiers

PMID39386185
PMCPMC11460570

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.