Evidence map›Paper›PMID 39386440›Full record

ArticlebioRxiv : the preprint server for biology2024

Distinct regulatory mechanisms by the nuclear Argonautes HRDE-1 and NRDE-3 in the soma of

Hector Mendoza, Eshna Jash, Michael B Davis, Rebecca A Haines, Sarah Van Diepenbos, Györgyi Csankovszki

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Eshna Jash
Michael B Davis
Rebecca A Haines
Sarah Van Diepenbos
Györgyi CsankovszkiORCID 0000-0001-5918-034X

Funding

Michigan IRACDA: Training Future Professors of Engineering and PhysiologyK12GM111725 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BROOKS, SUSAN V, SEPT, DAVID · 2016 to 2025
$7.9M
The gene regulatory functions of condensinR35GM149543 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Gyorgyi Csankovszki · 2023 to 2026
$1.8M
Gene regulatory functions of condensinR01GM133858 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CSANKOVSZKI, GYORGYI · 2020 to 2021
$602k
NIGMS NIH HHS K12 GM111725NIGMS NIH HHS R01 GM133858NIGMS NIH HHS R35 GM149543
6 · The paper itself

Abstract

RNA interference is a conserved silencing mechanism that depends on the generation of small RNA molecules that disrupt synthesis of their corresponding transcripts. Nuclear RNA interference is a unique process that triggers regulation through epigenetic alterations to the genome. This pathway has been extensively characterized in ARTICLE SUMMARY: This study examines the transcriptional consequences during the disruption of the nuclear RNAi silencing mechanism in

Identifiers

PMID39386440
PMCPMC11463658

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.