Evidence map›Paper›PMID 39386553›Full record

ArticlebioRxiv : the preprint server for biology2024

Transcriptomic and histological characterization of telocytes in the human dorsal root ganglion.

Rainer V Haberberger, Dusan Matusica, Stephanie Shiers, Ishwarya Sankaranarayanan, Theodore J Price

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Rainer V HaberbergerDepartment of Anatomy and Pathology, School of Biomedicine, The University of Adelaide, Adelaide, Australia.
Dusan MatusicaAnatomy, Histology & Pathology, College of Medicine and Public Health, Flinders University, Adelaide, Australia.
Stephanie ShiersDepartment of Neuroscience, Center for Advanced Pain Studies, The University of Texas at Dallas. Richardson, TX.
Ishwarya SankaranarayananDepartment of Neuroscience, Center for Advanced Pain Studies, The University of Texas at Dallas. Richardson, TX.
Theodore J PriceDepartment of Neuroscience, Center for Advanced Pain Studies, The University of Texas at Dallas. Richardson, TX.ORCID 0000-0002-6971-6221

Funding

Mechanistic underpinnings of chronic low back painU19NS130608 · NINDS · UNIVERSITY OF TEXAS DALLAS · PI Michele Curatolo, Patrick M Dougherty · 2022 to 2026
$13.6M
NINDS NIH HHS U19 NS130608
6 · The paper itself

Abstract

Telocytes are interstitial cells with long processes that cover distances in tissues and likely coordinate interacts with other cell types. Though present in central and peripheral neuronal tissues, their role remains unclear. Dorsal root ganglia (DRG) house pseudounipolar afferent neurons responsible for signals such as temperature, proprioception and nociception. This study aimed to investigate the presence and function of telocytes in human DRG by investigating their transcriptional profile, location and ultrastructure. Sequencing data revealed CD34 and PDGFRA expressing cells comprise roughly 1.5-3% of DRG cells. Combined expression of

Indexed as

dorsal root ganglionhumantelocyte

Identifiers

PMID39386553
PMCPMC11463542

What Socratic holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.