Evidence map›Paper›PMID 39390665›Full record

ReviewJournal of toxicology and environmental health. Part B, Critical reviews2025

Incorporating new approach methods (NAMs) data in dose-response assessments: The future is now!

En-Hsuan Lu, Ivan Rusyn, Weihsueh A Chiu

Abstract readReview
In one paragraph

Review in Journal of toxicology and environmental health. Part B, Critical reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. A workflow for human health hazard evaluation using transcriptomic data and Key Characteristics-based gene sets.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Article
  8. The Toxicity of Microplastics Explorer (ToMEx) 2.0.Microplastics and nanoplastics · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

En-Hsuan LuInterdisciplinary Faculty of Toxicology and Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX, USA.
Ivan RusynInterdisciplinary Faculty of Toxicology and Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX, USA.
Weihsueh A ChiuInterdisciplinary Faculty of Toxicology and Department of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX, USA.

Funding

Single cell, multi-parametric high throughput platform to classify endocrine disruptor potential of mixturesP42ES027704 · NIEHS · TEXAS A&M UNIVERSITY · PI Ivan Rusyn · 2017 to 2026
$21.2M
Texas A&M Center for Environmental Health Research (TiCER)P30ES029067 · NIEHS · TEXAS A&M UNIVERSITY · PI Natalie M Johnson · 2019 to 2026
$13.0M
Chromatin regions, genes and pathways that confer susceptibility to chemical-induced DNA damageR01ES029911 · NIEHS · TEXAS A&M AGRILIFE RESEARCH · PI RUSYN, IVAN, THREADGILL, DAVID W. · 2019 to 2023
$3.3M
NIEHS NIH HHS P30 ES029067NIEHS NIH HHS P42 ES027704NIEHS NIH HHS R01 ES029911
6 · The paper itself

Abstract

Regulatory dose-response assessments traditionally rely on

Indexed as

Dose-Response Relationship, DrugAnimalsHumansRisk AssessmentToxicity TestsToxicokineticsdose–response assessmentnew approach methodologiesRegulatory sciencerisk assessment

Identifiers

PMID39390665
PMCPMC11614695

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.