ReviewFrontiers in aging neuroscience2024
Mechanisms underlying delirium in patients with critical illness.
Review in Frontiers in aging neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- In-bed cycling for adult intensive care patients: A systematic review and meta-analysis.Medicine · 2026Pooled it
- Effect of Intraoperative Intravenous Lidocaine on Postoperative Delirium in Elderly Patients Undergoing Posterior Lumbar Interbody Fusion.Drug design, development and therapy · 2026Trial
- Delirium in the oncology intensive care unit: Risk, recognition, and recovery strategies.World journal of critical care medicine · 2026Review
- Effectiveness of Non-Pharmacological Interventions for the Prevention of Postoperative Delirium in Critically Ill Adult Patients: A Systematic Review and Meta-Analysis.Nursing reports (Pavia, Italy) · 2026Review
- Long-Term Cognitive and Functional Outcomes of Anesthesia and Surgery in Patients with Dementia.Healthcare (Basel, Switzerland) · 2026Review
- Development and Validation of an Interpretable Machine Learning Model for Predicting ICU-Acquired Weakness in Postoperative Patients.Nursing in critical care · 2026Article
- Association between stress hyperglycemia ratio and 72-hour delirium in critically ill patients: A retrospective cohort study from the MIMIC-IV database.Metabolism open · 2026Article
- From Sensory Deprivation to Psychosis: Environmental Mechanisms of Delirium in Dementia-An Eight-Year Retrospective Longitudinal Case Report and Narrative Review.Healthcare (Basel, Switzerland) · 2026Article
- Inflammatory Biomarkers and Delirium Severity in Critically Ill Adults: A Prospective Single-Center Cohort Study.Journal of clinical medicine · 2026Article
- Previous-day physical restraint duration as a bedside signal for following-day delirium: a retrospective patient-day analysis in a mixed ICU.Journal of intensive care · 2026Article
- Early Risk Stratification of Delirium in Intermediate Care Units and Its Impact on 30-Day Mortality: A Decision-Tree Analysis.Clinics and practice · 2026Article
- Perioperative interventions in preventing postoperative delirium following orthopaedic surgery in the elderly: a Bayesian network meta-analysis.Journal of orthopaedic translation · 2026Review
- Preoperative hyponatremia is associated with increased postoperative complications and short- to long-term mortality in geriatric hip fracture patients: a retrospective cohort study.BMC geriatrics · 2026Article
- Pharmacological Incongruity of Lacosamide in the Management of Delirium Complicated by Ileus.Neuropsychopharmacology reports · 2026Article
- Review
- Nomogram and machine learning models for predicting the risk of delirium in ICU patients with NSTEMI.Medicine · 2026Article
- Animal models of delirium: a narrative review.Translational psychiatry · 2026Review
- The Effect of Family Voice Interventions on Delirium Incidence and Duration in Adult ICU Patients: A Systematic Review and Meta-Analysis.Nursing in critical care · 2026Observational
- High glucose-to-lymphocyte ratio increases the risk of delirium and all-cause mortality in intensive care unit patients.Scientific reports · 2026Article
- Neurological Complications in Intensive Care Units: From Delirium to Long-Term Cognitive Dysfunction-A Narrative Review.Journal of clinical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Delirium is an acute, global cognitive disorder syndrome, also known as acute brain syndrome, characterized by disturbance of attention and awareness and fluctuation of symptoms. Its incidence is high among critically ill patients. Once patients develop delirium, it increases the risk of unplanned extubation, prolongs hospital stay, increases the risk of nosocomial infection, post-intensive care syndrome-cognitive impairment, and even death. Therefore, it is of great importance to understand how delirium occurs and to reduce the incidence of delirium in critically ill patients. This paper reviews the potential pathophysiological mechanisms of delirium in critically ill patients, with the aim of better understanding its pathophysiological processes, guiding the formulation of effective prevention and treatment strategies, providing a basis for clinical medication.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.