Evidence map›Paper›PMID 39391797›Full record

ArticleBrain, behavior, & immunity - health2024

Cardiovascular and kidney diseases are positively associated with neuroinflammation and reduced brain-derived neurotrophic factor in patients with severe COVID-19.

Rafael R Ferreira, Ronaldo B Martins, Isabela Pires, Bruno L Marques, Karla C M Costa, Pedro H C Lirio, Davi S Scomparin, Franciele F Scarante, Sabrina S Batah, Jaime E C Hallak and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain, behavior, & immunity - health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Rafael R FerreiraDepartment of Pharmacology- Ribeirão Preto Medical School- University of São Paulo, Ribeirão Preto, São Paulo, Brazil, 3900, Bandeirantes Avenue- Monte Alegre- Ribeirão Preto-SP-Brazil - 14049-900.
Ronaldo B MartinsDepartment of Cell and Molecular Biology, Ribeirão Preto School of Medicine, University of Sao Paulo, Ribeirão Preto, 3900, Bandeirantes Avenue- Monte Alegre- Ribeirão Preto-SP-Brazil, 14049-900, São Paulo, Brazil.
Isabela PiresDepartment of Pharmacology- Ribeirão Preto Medical School- University of São Paulo, Ribeirão Preto, São Paulo, Brazil, 3900, Bandeirantes Avenue- Monte Alegre- Ribeirão Preto-SP-Brazil - 14049-900.
Bruno L MarquesDepartment of Pharmacology- Ribeirão Preto Medical School- University of São Paulo, Ribeirão Preto, São Paulo, Brazil, 3900, Bandeirantes Avenue- Monte Alegre- Ribeirão Preto-SP-Brazil - 14049-900.
Karla C M CostaDepartment of Pharmacology- Ribeirão Preto Medical School- University of São Paulo, Ribeirão Preto, São Paulo, Brazil, 3900, Bandeirantes Avenue- Monte Alegre- Ribeirão Preto-SP-Brazil - 14049-900.
Pedro H C LirioDepartment of Pharmacology- Ribeirão Preto Medical School- University of São Paulo, Ribeirão Preto, São Paulo, Brazil, 3900, Bandeirantes Avenue- Monte Alegre- Ribeirão Preto-SP-Brazil - 14049-900.
Davi S ScomparinDepartment of Pharmacology- Ribeirão Preto Medical School- University of São Paulo, Ribeirão Preto, São Paulo, Brazil, 3900, Bandeirantes Avenue- Monte Alegre- Ribeirão Preto-SP-Brazil - 14049-900.
Franciele F ScaranteDepartment of Pharmacology- Ribeirão Preto Medical School- University of São Paulo, Ribeirão Preto, São Paulo, Brazil, 3900, Bandeirantes Avenue- Monte Alegre- Ribeirão Preto-SP-Brazil - 14049-900.
Sabrina S BatahDepartment of Pathology and Legal Medicine, Ribeirão Preto Medical School, University of São Paulo, 3900, Bandeirantes Avenue - Monte Alegre- Ribeirão Preto-SP-Brazil, 14049-900, Brazil.
Jaime E C HallakDepartment of Neuroscience and Behavior, Faculty of Medicine of Ribeirão Preto, University of São Paulo, 2650, Tenente Catão Roxo Street - Monte Alegre, Ribeirão Preto - SP- Brazil, 14051-140, São Paulo, Brazil.
Jose A CrippaDepartment of Neuroscience and Behavior, Faculty of Medicine of Ribeirão Preto, University of São Paulo, 2650, Tenente Catão Roxo Street - Monte Alegre, Ribeirão Preto - SP- Brazil, 14051-140, São Paulo, Brazil.
Livia C M RodriguesDepartment of Physiological Sciences, Health Sciences Center, Universidade Federal do Espírito Santo, Vitória 1468, Marechal Campos Avenue - Maruípe, Vitória, ES, 29047-105, Brazil.
Rita C TostesDepartment of Pharmacology- Ribeirão Preto Medical School- University of São Paulo, Ribeirão Preto, São Paulo, Brazil, 3900, Bandeirantes Avenue- Monte Alegre- Ribeirão Preto-SP-Brazil - 14049-900.
Alexandre T FabroDepartment of Pathology and Legal Medicine, Ribeirão Preto Medical School, University of São Paulo, 3900, Bandeirantes Avenue - Monte Alegre- Ribeirão Preto-SP-Brazil, 14049-900, Brazil.
Eurico ArrudaDepartment of Cell and Molecular Biology, Ribeirão Preto School of Medicine, University of Sao Paulo, Ribeirão Preto, 3900, Bandeirantes Avenue- Monte Alegre- Ribeirão Preto-SP-Brazil, 14049-900, São Paulo, Brazil.
Alline C CamposDepartment of Pharmacology- Ribeirão Preto Medical School- University of São Paulo, Ribeirão Preto, São Paulo, Brazil, 3900, Bandeirantes Avenue- Monte Alegre- Ribeirão Preto-SP-Brazil - 14049-900.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Even though respiratory dysfunctions are the primary symptom associated with SARS-CoV-2 infection, cerebrovascular events, and neurological symptoms are described in many patients. However, the connection between the neuroimmune profile and the lung's inflammatory condition during COVID-19 and its association with the neurological symptoms reported by COVID-19 patients still needs further exploration. The present study characterizes the SARS-CoV-2 infectivity profile in

Indexed as

BDNFCardiovascular diseaseKidney diseaseNeuroinflammationSARS-CoV-2Severe COVID-19

Identifiers

PMID39391797
PMCPMC11466569

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.