Evidence map›Paper›PMID 39394603›Full record

ArticleBMC geriatrics2024

Investigating the effects of indoor lighting on measures of brain health in older adults: protocol for a cross-over randomized controlled trial.

Kevin A Mazurek, Linhao Li, Robert J Klein, Shengliang Rong, Aidan F Mullan, David T Jones, Erik K St Louis, Gregory A Worrell, Christina Y Chen

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05978934 (Determining How Indoor Lighting Affects the Brain Health of Older Adults), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05978934 naunknown statusnot on this map

Determining How Indoor Lighting Affects the Brain Health of Older Adults

TypeinterventionalSponsorWell Living Lab, Inc.Ran2023 to 2023Enrolled70ConditionsSleep, Physical Activity, Cognitive Function, Social IsolationArmsStatic Lighting Condition (L1), Dynamic Lighting Condition (L2), Dynamic Lighting Condition (L3)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kevin A Mazurek *Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Linhao Li *Well Living Lab, Rochester, MN, USA. Linhao.li@delos.com.
Robert J KleinWell Living Lab, Rochester, MN, USA.
Shengliang RongDelos Living LLC, New York, NY, USA.
Aidan F MullanDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
David T JonesDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Erik K St LouisDepartment of Neurology, Mayo Clinic, Rochester, MN, USA.
Gregory A WorrellDepartment of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA.
Christina Y ChenDepartment of Community Internal Medicine, Mayo Clinic, Rochester, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe worldwide number of adults aged 60 years and older is expected to double from 1 billion in 2019 to 2.1 billion by 2050. As the population lives longer, the rising incidence of chronic diseases, cognitive disorders, and behavioral health issues threaten older adults' health span. Exercising, getting sufficient sleep, and staying mentally and socially active can improve quality of life, increase independence, and potentially lower the risk for Alzheimer's disease or other dementias. Nonpharmacological approaches might help promote such behaviors. Indoor lighting may impact sleep quality, physical activity, and cognitive function. Dynamically changing indoor lighting brightness and color throughout the day has positive effects on sleep, cognitive function, and physical activity of its occupants. The aim of this study is to investigate how different indoor lighting conditions affect such health measures to promote healthier aging.

methodsThis protocol is a randomized, cross-over, single-site trial followed by an exploratory third intervention. Up to 70 older adults in independent living residences at a senior living facility will be recruited. During this 16-week study, participants will experience three lighting conditions. Two cohorts will first experience a static and a dynamic lighting condition in a cluster-randomized cross-over design. The static condition lighting will have fixed brightness and color to match lighting typically provided in the facility. For the dynamic condition, brightness and color will change throughout the day with increased brightness in the morning. After the cross-over, both cohorts will experience another dynamic lighting condition with increased morning brightness to determine if there is a saturation effect between light exposure and health-related measures. Light intake, sleep quality, and physical activity will be measured using wearable devices. Sleep, cognitive function, mood, and social engagement will be assessed using surveys and cognitive assessments. DISCUSSION: We hypothesize participants will have better sleep quality and greater physical activity during the dynamic lighting compared to the static lighting condition. Additionally, we hypothesize there is a maximal threshold at which health-outcomes improve based on light exposure. Study findings may identify optimal indoor lighting solutions to promote healthy aging for older adults.

trial registrationClinicalTrials.gov Identifier: NCT05978934.

Indexed as

Cross-Over StudiesLightingAgedBrainCognitionExerciseFemaleHumansIndependent LivingMaleMiddle AgedRandomized Controlled Trials as TopicSleep QualityBrain healthCognitive functionHealthy agingIndoor lightingPhysical activitySleepSocial engagement

Identifiers

PMID39394603
PMCPMC11468298

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.