ArticleACS omega2024
A 3-Dimensional Scaffolding System Recapitulates the Hierarchical Osteon Structure.
Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Bone Organoids: A Novel Tool for Modeling and Managing Skeletal Disorders in Diabetes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The bone is composed of solid cortical bone and honeycomb-like trabecular bone. Although the cortical bone provides the substantial mechanical strength of the bone, few studies have focused on its regeneration. As the structural and functional units of the cortical bone, osteons play critical roles in bone turnover. Composed of osteocytes, lamellae, lacunocanalicular network, and Haversian canals, osteons exhibit a delicate and hierarchical architecture. Studies have attempted to reconstruct the osteonal structure with artificial approaches; however, hardly the four elements were recapitulated simultaneously. In this work, a series of bioengineering techniques, including electrospinning, micropatterning, and laser-directed microfabrication, were employed to develop a three-dimensional scaffolding system, which successfully recapitulated the osteon structure
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.