Evidence map›Paper›PMID 39399248›Full record

ArticleACG case reports journal2024

Successful Use of Fecal Microbiota Transplantation in Management of Nonobstructive Recurrent Cholangitis Following Total Pancreatectomy and Islet Autotransplant.

Adam Scott, Alexander Khoruts, Martin L Freeman, Greg Beilman, Karthik Ramanathan, Melena D Bellin, Guru Trikudanathan

Registry-linked trialAbstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07509346 (Multicenter Clinical Trial to Evaluate the Efficacy and Safety of Fecal Microbiota Transplantation Versus Standard Treatment in Patients With Recurrent Non-Obstructive Acute Cholangitis - COLANBIOTA Trial), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07509346 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Multicenter Clinical Trial to Evaluate the Efficacy and Safety of Fecal Microbiota Transplantation Versus Standard Treatment in Patients With Recurrent Non-Obstructive Acute Cholangitis - COLANBIOTA Trial

TypeinterventionalSponsorPuerta de Hierro University HospitalRan2026 to 2029Enrolled44ConditionsCholangitis Acute, RecurrenceArmsFecal Microbial Transplantation
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Non-obstructive recurrent cholangitis following biliary reconstruction for benign indications: A tertiary care experience.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adam ScottUniversity of Minnesota Medical School, Minneapolis, MN.
Alexander KhorutsUniversity of Minnesota Medical Center, Minneapolis, MN.
Martin L FreemanUniversity of Minnesota Medical Center, Minneapolis, MN.
Greg BeilmanUniversity of Minnesota Medical Center, Minneapolis, MN.
Karthik RamanathanUniversity of Minnesota Medical Center, Minneapolis, MN.
Melena D BellinUniversity of Minnesota Medical Center, Minneapolis, MN.
Guru TrikudanathanUniversity of Minnesota Medical Center, Minneapolis, MN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations in the gut microbiome have been implicated in various pathologies. Fecal microbiota transplantation (FMT) has been offered as a novel treatment for conditions implicated in the disruption of the gut-microbiota axis. This case report details the successful treatment of recurrent nonobstructive cholangitis following a single FMT application in a patient who had previously undergone a hepatobiliary tract surgical diversion. Cholangitis was suspected secondary to reflux of an altered microbiome into the surgically reanastomosed biliary tract, and FMT was justified based on the history of recurrent

Indexed as

cholangitisclostridiodes difficlefecal microbiota transplantationfecal transplantFMTgut-microbiota axishepatobiliarymicrobiomepancreasetotal pancreatectomy islet autotransplantTPIAT

Identifiers

PMID39399248
PMCPMC11469898

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.