Evidence map›Paper›PMID 39399445›Full record

ArticleRare tumors2024

Exploration of the causative gene in a case of multiple nevoid basal cell carcinoma: A case report.

Yutong Liu, Xuejun Gao, Lianjing Cao, Jizhen Ren, Yuanxin Miao, Xia Cai

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Rare tumors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yutong LiuPlastic Surgery, Affiliated Hospital of Qingdao University, Qingdao, China.
Xuejun GaoThyroid Surgery, Affiliated Hospital of Qingdao University, Qingdao, China.
Lianjing CaoGastroenterology Department, Affiliated Hospital of Qingdao University, Qingdao, China.
Jizhen RenPlastic Surgery, Affiliated Hospital of Qingdao University, Qingdao, China.
Yuanxin MiaoPlastic Surgery, Affiliated Hospital of Qingdao University, Qingdao, China.
Xia CaiPlastic Surgery, Affiliated Hospital of Qingdao University, Qingdao, China.ORCID https://orcid.org/0009-0008-6695-3775

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nevoid basal cell carcinoma syndrome is a rare autosomal dominant disorder characterized by a diverse clinical presentation, which includes developmental abnormalities and tumorigenesis that can impact multiple organ systems. Basal cell carcinoma is the most common and characteristic clinical presentation in patients with NBCCS. There are three identified causative genes for this disease, the PTCH1 gene located at 9q22-31, the PTCH2 gene at 1p32-34, and the SUFU gene at 10q24.32. In this paper, we report a case of multiple nevoid basal cell carcinoma. The mutated gene in this patient was determined to be the ELP1 gene located on chromosome 9. This patient's ELP1 gene mutation may contribute to the development of multiple nevoid basal cell carcinomas on the face.

Indexed as

basal cell nevus syndromeELP1 geneGorlin–Goltz syndromeGorlin syndromeMultiple nevoid basal cell carcinomanevoid basal cell carcinoma syndromeskin cancer

Identifiers

PMID39399445
PMCPMC11468328

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.