Evidence map›Paper›PMID 39400995›Full record

ArticleArthritis care & research2025

Limitations in Activities of Daily Living Among Individuals With Systemic Lupus Erythematosus.

Laura C Plantinga, C Barrett Bowling, Bradley D Pearce, Courtney Hoge, Charmayne Dunlop-Thomas, S Sam Lim, Patricia P Katz, Jinoos Yazdany

Abstract read
In one paragraph

Article in Arthritis care & research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laura C PlantingaUniversity of California, San Francisco.ORCID 0000-0003-0809-8981
C Barrett BowlingDurham Veterans Affairs Medical Center and Duke University, Durham, North Carolina.
Bradley D PearceEmory University, Atlanta, Georgia.
Courtney HogeEmory University, Atlanta, Georgia.
Charmayne Dunlop-ThomasEmory University, Atlanta, Georgia.
S Sam LimEmory University, Atlanta, Georgia.ORCID 0000-0003-2361-0787
Patricia P KatzUniversity of California, San Francisco.ORCID 0000-0002-8146-2519
Jinoos YazdanyUniversity of California, San Francisco.ORCID 0000-0002-3508-4094

Funding

RESOURCE-BASED CENTER FOR THE ADVANCEMENT OF PRECISION MEDICINE IN RHEUMATOLOGYP30AR070155 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Mary C Nakamura · 2016 to 2026
$8.2M
Burden, correlates, and outcomes of poor cognitive and physical functioning in the lupus populationR01AG061179 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PLANTINGA, LAURA · 2019 to 2024
$1.6M
ACL HHS U01DP006698CDC HHS 1U01DP006698NCCDPHP CDC HHS U01 DP006698NIAMS NIH HHS P30 AR070155NIA NIH HHS R01 AG061179NIA NIH HHS R01AG061179
6 · The paper itself

Abstract

objectiveWe aimed to estimate the burden and identify potential correlates of limitations in activities of daily living (ADLs) among persons with systemic lupus erythematosus (SLE).

methodsIndividuals with SLE were recruited from a population-based cohort (October 2019 to May 2022) and reported their ability to independently perform various instrumental ADLs (IADLs) and basic ADLs (BADLs) via survey. Limitations were defined as having at least some difficulty performing at least one of the IADLs or BADLs. Descriptive statistics were calculated, and associations (adjusted odds ratios [aORs]) of various participant characteristics with IADL and BADL limitations were assessed with logistic regression adjusting for age, sex, and race.

resultsThe mean age of the 436 participants was 46.2 years; most were female (91.7%) and Black (82.8%). More than half (56.2%) reported limitations in IADLs, most commonly housekeeping (50.7%), laundry (37.2%), and shopping (33.0%); 43.8% reported limitations in independently performing BADLs, most commonly transferring (26.6%), bathing (25.3%), dressing (24.4%), and continence (22.0%). Higher disease activity (greater than or equal to vs less than the median) was strongly associated with IADLs (aOR 6.49, 95% confidence interval [CI] 4.15-10.2) and BADLs (aOR 7.35, 95% CI 4.70-11.5), along with higher depression and perceived stress scores, lower educational attainment and income, and older age.

conclusionIADL and BADL limitations may be common in individuals with SLE and more prevalent among those who report higher disease activity, depressive symptoms, and lower income and among those who are older. Research to support evidence-based strategies for improvement in quality of life and maintenance of independence in the older SLE population is warranted.

Indexed as

Activities of Daily LivingLupus Erythematosus, SystemicAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedQuality of Life

Identifiers

PMID39400995
PMCPMC11932797

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.