Evidence map›Paper›PMID 39401078›Full record

ArticleeLife2024

A comparative study of the cryo-EM structures of

Ester Vazquez-Fernandez, Jing Yang, Ziguo Zhang, Antonina E Andreeva, Paul Emsley, David Barford

Abstract readComparative Study
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Cryo-EM structures of apo-APC/C and APC/CNature communications · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ester Vazquez-FernandezMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
Jing YangMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
Ziguo ZhangMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
Antonina E AndreevaMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
Paul EmsleyMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
David BarfordMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.ORCID https://orcid.org/0000-0001-8810-950X

Funding

Cancer Research UK C576/A14109Medical Research Council MC_UP_1201/6
6 · The paper itself

Abstract

The anaphase-promoting complex/cyclosome (APC/C) is a large multi-subunit E3 ubiquitin ligase that controls progression through the cell cycle by orchestrating the timely proteolysis of mitotic cyclins and other cell cycle regulatory proteins. Although structures of multiple human APC/C complexes have been extensively studied over the past decade, the

Indexed as

Anaphase-Promoting Complex-CyclosomeCryoelectron MicroscopySaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsHumansPhosphorylationProtein ConformationAnaphase-Promoting Complex-CyclosomeSaccharomyces cerevisiae ProteinsAPC/Ccell cyclechromosomesgene expressionmitosisS. cerevisiaeubiquitination

Identifiers

PMID39401078
PMCPMC11473103

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.