Evidence map›Paper›PMID 39402634›Full record

ArticleLipids in health and disease2024

Association between body roundness index and risk of osteoarthritis: a cross-sectional study.

Xudong Wang, Zijian Guo, Meng Wang, Chuan Xiang

Abstract read
In one paragraph

Article in Lipids in health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  12. Relative Fat Mass and Psoriasis Risk: Evidence from NHANES 2009-2014.Journal of multidisciplinary healthcare · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xudong Wang *Department of Orthopedics, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, P.R. China.
Zijian Guo *Department of Orthopedics, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, P.R. China.
Meng WangDepartment of Orthopedics, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, P.R. China.
Chuan XiangDepartment of Orthopedics, The Second Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, P.R. China. chuanxiang@sxmu.edu.cn.

Funding

This study was supported by the Central Guided Local Science and Technology Development Funds No. YDZJSX20231A062
6 · The paper itself

Abstract

backgroundThe link between body roundness index (BRI) and osteoarthritis (OA) has yet to be validated. Our aim was to explore this connection between BRI and OA risk.

methodsThis cross-sectional study utilized the 1999-2018 National Health and Nutrition Examination Survey retrieved data. To assess the association between BRI and OA risk, we performed weighted multivariable regression analysis (MVRA), with smooth curve fitting for potential nonlinear association and subgroup analysis and interaction tests for relationships in specific subgroups. A 7:3 ratio was adopted for the random division of the acquired data into training and validation sets. Subsequently, least absolute shrinkage and selection operator regression, along with MVRA, were conducted for the training set to isolate variables for a prediction model. This model was visualized using the nomogram and was followed by evaluation. Finally, the validation set was utilized to validate the model.

resultsThis study enrolled 12,946 individuals. Following the adjustment for all covariables, OA risk increased by 18% with every unit rise in BRI (odd ratio [OR] = 1.18; 95% confidence interval [CI]: 1.13-1.23; P < 0.0001). Upon regarding BRI as a categorical variable, it was divided into quartiles for subsequent analysis. In comparison to quartile 1, the risk of OA was increased in quartile 2 (OR = 1.58; 95% CI: 1.22-2.03; P = 0.0006), quartile 3 (OR = 1.83; 95% CI: 1.40-2.40; P < 0.0001) and quartile 4 (OR = 2.70; 95% CI: 1.99-3.66; P < 0.0001). Smooth curve fitting revealed no non-linear relationships. None of the subgroups showed a statistically significant interaction (all P > 0.05). After selecting the variables, a prediction model was developed. The prediction model exhibited favorable discriminatory power, high accuracy, and potential clinical benefits in training and validation sets.

conclusionsThe BRI was positively associated with OA risk. Our predictive model demonstrated that combining BRI with other easily accessible factors was helpful in assessing and managing high-risk OA groups.

Indexed as

OsteoarthritisAdultAgedBody Mass IndexCross-Sectional StudiesFemaleHumansMaleMiddle AgedNutrition SurveysOdds RatioRisk FactorsBody roundness indexCross-sectional studyNational Health and Nutrition Examination SurveyOsteoarthritis

Identifiers

PMID39402634
PMCPMC11472493

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.