Evidence map›Paper›PMID 39402877›Full record

Trial reportJournal of clinical periodontology2025

Effect of a Whole-Food Plant-Based Diet on Periodontal Parameters in Patients With Cardiovascular Risk Factors: A Secondary Sub-Analysis of a Randomized Clinical Trial.

C L Pappe, S Lutzenberger, K Goebler, S Meier, M Jeitler, A Michalsen, H Dommisch

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of clinical periodontology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03901183 (Plant-based Nutrition for Patients With Cardiovascular Risk Factors - a Randomized Controlled Trial), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03901183 nacompletednot on this map

Plant-based Nutrition for Patients With Cardiovascular Risk Factors - a Randomized Controlled Trial

TypeinterventionalSponsorCharite University, Berlin, GermanyRan2019 to 2021Enrolled70ConditionsMetabolic Syndrome, Cardiovascular Risk Factor, Overweight and Obesity, Hypertension,EssentialArmsPlant-based Diet
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

C L PappeDepartment of Periodontology, Oral Medicine and Oral Surgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.ORCID 0000-0002-0645-704X
S LutzenbergerDepartment of Periodontology, Oral Medicine and Oral Surgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.
K GoeblerDepartment of Mathematics, Technical University of Munich - TUM School of Computation, Information and Technology, Munich, Germany.
S MeierDepartment of Periodontology, Oral Medicine and Oral Surgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.
M JeitlerCharité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
A MichalsenCharité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
H DommischDepartment of Periodontology, Oral Medicine and Oral Surgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.ORCID 0000-0003-1043-2651

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the effect of a 16-week whole-food plant-based diet (WPBD) on periodontal parameters in patients with increased cardiometabolic risk. MATERIALS AND

methodsA total of 36 participants from a randomized clinical trial received additional periodontal assessment. The intervention group (n = 17) followed a WPBD for 16 weeks, whereas the control group (CG) (n = 19) was instructed not to change their diet. Measurements were assessed at baseline (t1), week 8 (t2) and week 16 (t3). Periodontal examination included bleeding on probing (BOP), periodontal inflamed surface area (PISA) and plaque index (PI) on six index teeth, salivary pH and matrix-matalloproteinase-8 (MMP-8).

resultsAt t3, the mean PISA of the index teeth was reduced by 32 mm

conclusionA trend towards stabilization of the inflammatory parameters (BOP, PISA) was observed in the WPBD group. Because of the non-significant changes within the groups, this study highlights the imperative for future studies. CLINICALTRIALS: GOV IDENTIFIER: NCT03901183.

Indexed as

Matrix Metalloproteinase 8AdultAgedCardiovascular DiseasesDental Plaque IndexDiet, Plant-BasedDiet, VegetarianFemaleHeart Disease Risk FactorsHumansHydrogen-Ion ConcentrationMaleMiddle AgedPeriodontal IndexSalivaMatrix Metalloproteinase 8bleeding on probinghypertensionperiodontal inflammationwhole‐food plant‐based diet

Identifiers

PMID39402877
PMCPMC11671171

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.