Evidence map›Paper›PMID 39402905›Full record

ArticleJournal of surgical oncology2024

Visceral fat area and subcutaneous fat area as measures of body composition in soft tissue sarcoma.

Eric Robles Garibay, Sylvia M Cruz, Sean J Judge, Arta M Monjazeb, Steven W Thorpe, William J Murphy, Jing Lyu, Shuai Chen, Cyrus P Bateni, Robert J Canter

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eric Robles GaribayDepartment of Surgery, Division of Surgical Oncology, University of California Davis, Sacramento, California, USA.
Sylvia M CruzDepartment of Surgery, Division of Surgical Oncology, University of California Davis, Sacramento, California, USA.ORCID http://orcid.org/0000-0001-9007-6639
Sean J JudgeDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Arta M MonjazebDepartment of Radiation Oncology, University of California Davis, Sacramento, California, USA.
Steven W ThorpeDepartment of Orthopedic Surgery, Division of Orthopedic Oncology, University of California Davis, Sacramento, California, USA.
William J MurphyDepartment of Dermatology, University of California, Davis, Sacramento, California, USA.
Jing LyuDepartment of Public Health Sciences, Division of Biostatistics, University of California Davis, Sacramento, California, USA.
Shuai ChenDepartment of Public Health Sciences, Division of Biostatistics, University of California Davis, Sacramento, California, USA.
Cyrus P BateniDepartment of Radiology, Division of Musculoskeletal Radiology, University of California Davis, Sacramento, California, USA.
Robert J CanterDepartment of Surgery, Division of Surgical Oncology, University of California Davis, Sacramento, California, USA.ORCID http://orcid.org/0000-0002-3331-5418

Funding

Shared Resource ManagementP30CA093373 · UNIVERSITY OF CALIFORNIA DAVIS · 2002 to 2025
$10.6M
NCI NIH HHS P30 CA093373
6 · The paper itself

Abstract

BACKGROUND AND

objectivesSoft tissue sarcomas (STS) are a heterogenous group of malignancies of mesenchymal origin. Given recent data linking obesity as well as the pattern of fat distribution with cancer outcomes, we sought to investigate the association of visceral fat area (VFA) and subcutaneous fat area (SFA) with oncologic outcomes in patients with STS undergoing surgery.

methodsWe analyzed data from 88 patients with STS diagnosed from 2008 to 2022. Predictor variables included body mass index (BMI), VFA, and SFA. VFA and SFA were obtained from computed tomography of the abdomen and pelvis. Univariable and multivariable Cox regression analysis was used to analyze associations between predictor variables and overall survival and recurrence-free survival.

resultsAlthough BMI was closely correlated with VFA (r = 0.69, p < 0.0001) and SFA (r = 0.80, p < 0.0001), there was no significant association between high BMI, VFA or SFA, and worse oncologic outcomes.

conclusionsAlthough VFA and SFA are strongly correlated with BMI, we did not observe BMI nor imaging metrics of fat composition to be associated with worse oncologic outcomes. Further research is needed to elucidate any links between body fat content and metabolic or immune factors governing oncologic outcomes in STS.

Indexed as

Body CompositionBody Mass IndexIntra-Abdominal FatSarcomaSubcutaneous FatAdultAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetrospective StudiesSurvival Ratebody mass indexobesitysoft tissue sarcomasubcutaneous fat areavisceral fat area

Identifiers

PMID39402905
PMCPMC11753180

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.