Evidence map›Paper›PMID 39403022›Full record

ArticleUnited European gastroenterology journal2024

Impact of colorectal cancer screening programme on survival and employment in Taiwan: A nationwide analysis of real-world data.

Wei-Ying Chen, Yi-Peng Lu, Yu-Wen Chien, Li-Jung Elizabeth Ku, Jung-Der Wang

Abstract read
In one paragraph

Article in United European gastroenterology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wei-Ying ChenDepartment of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.ORCID 0000-0001-5074-3097
Yi-Peng LuDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Yu-Wen ChienDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Li-Jung Elizabeth KuDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.ORCID 0000-0002-4644-8439
Jung-Der WangDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.ORCID 0000-0002-3176-4500

Funding

National Science and Technology Council MOST 111-2314-B-006 -029-MY2National Science and Technology Council NSTC 112-2627-M-006-002
6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) leads to life loss and a significant economic burden, which could be reduced by CRC screening.

objectiveWe assessed the potential savings of lives and employment to evaluate the effectiveness of the Taiwan CRC Screening Programme.

methodsThrough interlinkages among Taiwan Cancer Registry, National Mortality Registry, Taiwan CRC Screening Database, and National Health Insurance claim data, we enroled patients with colorectal adenocarcinoma, aged 50-74 years and diagnosed during 2004-2017, and followed them up to 2018. Life expectancy (LE), lifetime employment duration (LED), loss-of-LE and loss-of-LED were calculated, compared with age-, sex- and calendar year-matched cohorts. Assuming no difference within a specific stage for screen-detected versus non-screen detected CRC and weighting them by different stage distributions, we compared the total loss-of-LE and loss-of-LED.

resultsThe cohort enroled 77,169 patients with colorectal adenocarcinoma, which included 31,728 women (mean [SD] age, 62.5 [7.1] years) and 45,441 men (mean [SD] age, 62.8 [6.8] years). The mean loss-of-LE and loss-of-LED in women were 6.0 (95% confidence interval [CI] 5.7-6.3) and 1.0 (95% CI 0.8-1.1) year(s), whereas those in men were 5.1 (95% CI 4.9-5.4) and 1.1 (95% CI 1.0-1.2) years, respectively. Among the cohort, 53,678 cases had the screening information. On average, screening potentially saved 2.9 (95% CI 2.6-3.2) years of life expectancy plus 0.5 (95% CI 0.4-0.6) years of employment per case in women and 2.7 (95% CI 2.5-3.0) years plus 0.6 (95% CI 0.5-0.7) years in men, respectively.

conclusionThe Taiwan CRC Screening Programme is associated with the savings of lives and employment duration. Future studies are warranted to evaluate the cost-effectiveness of beginning screening at a younger age after accounting for saving employment loss and possibly adjusting lead time bias.

Indexed as

Colorectal NeoplasmsEarly Detection of CancerEmploymentAdenocarcinomaAgedFemaleHumansLife ExpectancyMaleMass ScreeningMiddle AgedRegistriesTaiwancolorectal cancercolorectal cancer screeninglife expectancylifetime employment durationloss‐of‐life expectancyloss‐of‐lifetime employment durationTaiwan

Identifiers

PMID39403022
PMCPMC11652329

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.