Evidence map›Paper›PMID 39403117›Full record

ArticleBeilstein journal of nanotechnology2024

Dual-functionalized architecture enables stable and tumor cell-specific SiO

Iris Renata Sousa Ribeiro, Raquel Frenedoso da Silva, Romênia Ramos Domingues, Adriana Franco Paes Leme, Mateus Borba Cardoso

Abstract read
In one paragraph

Article in Beilstein journal of nanotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Anti-Scientifica · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Iris Renata Sousa RibeiroInstitute of Chemistry (IQ), University of Campinas (UNICAMP), Postal Code 13083- 970, Post Office Box 6154, Campinas, SP, Brazil.ORCID https://orcid.org/0000-0003-0929-5231
Raquel Frenedoso da SilvaBrazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy and Materials (CNPEM), Postal Code 13083-970, Campinas, Brazil.
Romênia Ramos DominguesBrazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Postal Code 13083-970, Campinas, Brazil.
Adriana Franco Paes LemeBrazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Postal Code 13083-970, Campinas, Brazil.ORCID https://orcid.org/0000-0001-7959-147X
Mateus Borba CardosoInstitute of Chemistry (IQ), University of Campinas (UNICAMP), Postal Code 13083- 970, Post Office Box 6154, Campinas, SP, Brazil.ORCID https://orcid.org/0000-0003-2102-1225

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most commercial anticancer nanomedicines are administered intravenously. This route is fast and precise as the drug enters directly into the systemic circulation, without undergoing absorption processes. When nanoparticles come into direct contact with the blood, however, they interact with physiological components that can induce colloidal destabilization and/or changes in their original biochemical identity, compromising their ability to selectively accumulate at target sites. In this way, these systems usually lack active targeting, offering limited therapeutic effectiveness. In the literature, there is a paucity of in-depth studies in complex environments to evaluate nanoparticle stability, protein corona formation, hemolytic activity, and targeting capabilities. To address this issue, fluorescent silica nanoparticles (SiO

Indexed as

colloidal stabilitycomplex mediafunctionalized nanoparticleshemolysistargeting tumor

Identifiers

PMID39403117
PMCPMC11472657

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.