Evidence mapPaperPMID 39403308Full record

ArticlePragmatic and observational research2024

Non-Alcoholic Steatohepatitis Patient Characterization and Real-World Management Approaches in Italy.

Elisabetta Bugianesi, Luca Miele, Giovanna Donnarumma, Katrine Grau, Mariarosaria Mancuso, Preethy Prasad, Andrea Leith, Victoria Higgins

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Article in Pragmatic and observational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Elisabetta BugianesiDivision of Gastroenterology, Department of Medical Sciences, University of Torino, AOU Città della Salute e della Scienza, Torino, Italy.
Luca MieleDipartimento di Scienze Mediche e Chirurgiche Addominali ed Endocrino Metaboliche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Giovanna DonnarummaNovo Nordisk SpA, Rome, Italy.
Katrine GrauNovo Nordisk A/S, Søborg, Denmark.
Mariarosaria MancusoNovo Nordisk SpA, Rome, Italy.
Preethy PrasadNovo Nordisk A/S, Søborg, Denmark.
Andrea LeithAdelphi Real World, Bollington, Cheshire, UK.
Victoria HigginsAdelphi Real World, Bollington, Cheshire, UK.ORCID 0000-0002-3901-7390

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although the estimated prevalence of non-alcoholic steatohepatitis (NASH) in Italy is 4-6%, little is known about patient characteristics and care pathways. Aim: To describe patient characteristics and management approaches for patients with NASH or suspected NASH in Italy. Methods: Data were drawn from the Adelphi Real World NASH Disease Specific Programme™, a cross-sectional survey of endocrinologists and gastroenterologists in Italy from January to March 2018. Physicians completed questionnaires for their next five consecutively consulting patients with NASH or suspected NASH. Analyses were descriptive. Results: Seventy-six physicians provided data on 380 patients. The mean age was 58.5 ± 11.1 years and the mean body mass index was 31.8 ± 5.5 kg/m Conclusion: Patients with NASH in Italy had high levels of obesity and comorbidities, while diagnosis and treatment frequently were not according to guidelines. Our data show an unmet need for more targeted diagnosis and treatment in Italian patients with NASH, in order to optimize outcomes.

Indexed as

NASH diagnosisNASH resource utilizationNASH treatment

Identifiers

PMID39403308
PMCPMC11472768

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.