Evidence map›Paper›PMID 39403398›Full record

ReviewFrontiers in nutrition2024

Therapeutic and preventive effects of astaxanthin in ischemic stroke.

Xu Wang, Hongyan Li, Gaihua Wang, Ziqiao He, Xueting Cui, Feiyu Song, Jinhua Li, Lin Zhang

Abstract readReview
In one paragraph

Review in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xu Wang *China-Japan Union Hospital, Jilin University, Changchun, Jilin, China.
Hongyan Li *Hospital of Stomatology, Jilin University, Changchun, Jilin, China.
Gaihua WangSchool of Public Health, Jilin University, Jilin, China.
Ziqiao HeSchool of Public Health, Jilin University, Jilin, China.
Xueting CuiSchool of Public Health, Jilin University, Jilin, China.
Feiyu SongJilin Connell Pharmaceutical Co., Ltd., Jilin, China.
Jinhua LiSchool of Public Health, Jilin University, Jilin, China.
Lin ZhangChina-Japan Union Hospital, Jilin University, Changchun, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic stroke poses a significant global health challenge with limited treatment options. Tissue plasminogen activator, the only effective medication, has strict restrictions, limiting its benefits only to a small number of patients. Astaxanthin, a natural carotenoid found in algae, shrimp, and crabs, has demonstrated promising neuroprotective properties in models of ischemic stroke. This article reviews the novel finding of neuroprotective impact of astaxanthin in ischemic stroke, highlighting its benefits in various protective mechanisms such as antioxidation, anti-inflammation, enhancement of DNA repair, anti-cell death, protection of blood-brain barrier, and promotion of neuronal survival. This analysis underscores the therapeutic and preventive potential of astaxanthin in ischemic stroke, positioning it as a prospective pharmaceutical agent against ischemic stroke.

Indexed as

astaxanthincarotenoidischemic strokeneuroprotective effectparthanatos

Identifiers

PMID39403398
PMCPMC11472662

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.