Evidence mapPaperPMID 39404382Full record

ReviewCells2024

The Modulatory Effects and Therapeutic Potential of Cannabidiol in the Gut.

Kevin Brown, Kyle Funk, Alexa Figueroa Barrientos, Ashly Bailey, Sarah Shrader, Wenke Feng, Craig J McClain, Zhao-Hui Song

Abstract readReview
In one paragraph

Review in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Targeting the LPI/GPR55 Axis in MAFLD and MASH: Novel Insights, Therapeutic Strategies and Future Directions.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kevin BrownCollege of Medicine and Life Sciences, The University of Toledo, Toledo, OH 43614, USA.
Kyle FunkDepartment of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY 40292, USA.
Alexa Figueroa BarrientosDepartment of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY 40292, USA.
Ashly BaileyDepartment of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY 40292, USA.
Sarah ShraderDepartment of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY 40292, USA.
Wenke FengDepartment of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
Craig J McClainDepartment of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY 40292, USA.ORCID 0000-0002-7219-8939
Zhao-Hui SongDepartment of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY 40292, USA.

Funding

Project 4 - Smita Ghare, PhDP20GM113226 · NIGMS · UNIVERSITY OF LOUISVILLE · 2021 to 2025
$6.9M
The Role of Nutrition in the Development/Progression of Alcohol-Induced Organ InjuryP50AA024337 · NIAAA · UNIVERSITY OF LOUISVILLE · 2021 to 2025
$4.2M
Cannabidiol as a treatment for alcoholic liver diseaseR21AA031172 · NIAAA · UNIVERSITY OF LOUISVILLE · PI WENKE FENG, ZHAO-HUI SONG · 2023 to 2023
$411k
University of Louisville Cancer Education ProgramR25CA134283 · NCI · UNIVERSITY OF LOUISVILLE · PI David W Hein, La Creis Renee Kidd · 2022 to 2022
$319k
NCI NIH HHS R25 CA134283NIAAA NIH HHS P50 AA024337NIAAA NIH HHS R21 AA031172NIGMS NIH HHS P20 GM113226NIH HHS P20GM113226NIH HHS P50AA024337NIH HHS R21AA031172NIH HHS R25CA134283
6 · The paper itself

Abstract

Cannabidiol (CBD) is a major non-psychotropic phytocannabinoid that exists in the

Indexed as

CannabidiolGastrointestinal TractAnimalsGastrointestinal MicrobiomeHumansCannabidiolcaco-2 cellcannabidiol (CBD)Crohn’s diseaseendocannabinoid systemgastrointestinal tractinflammatory bowel disease (IBD)microbiomeulcerative colitisΔ9-tetrahydrocannabinol (Δ9-THC)

Identifiers

PMID39404382
PMCPMC11475737

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.