Article in American journal of physiology. Gastrointestinal and liver physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Michael MomohSection of Surgical Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, United States.ORCID 0009-0006-7387-5192
Sudiksha Rathan-KumarSection of Surgical Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, United States.ORCID 0000-0003-2290-1582
Andreanna BurmanDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, United States.
Monica E BrownDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, United States.ORCID 0000-0002-8697-2702
Francisca AdeniranSection of Surgical Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, United States.
Cynthia RamosSection of Surgical Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, United States.
James R GoldenringSection of Surgical Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, United States.ORCID 0000-0002-7833-2940
Joseph T RolandSection of Surgical Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, United States.
Izumi KajiSection of Surgical Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, United States.ORCID 0000-0001-5395-0497
Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ben Ho Park · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MARY Kay WASHINGTON · 2002 to 2026
$29.9M
Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal CancerP50CA236733 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STEPHEN W. FESIK · 2019 to 2026
$19.6M
COngenital Diarrhea and Enteropathy (PediCODE) Consortium and BioRepositoryRC2DK118640 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI James Richard Goldenring, Izumi Kaji · 2019 to 2026
$14.8M
SMALL GTP BINDING PROTEINS IN GASTROINTESTINAL MUCOSAR01DK048370 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GOLDENRING, JAMES RICHARD · 1994 to 2025
$10.1M
Impacting the pathophysiology of malabsorption induced by Myosin Vb inactivating mutationsR01DK128190 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KAJI, IZUMI · 2021 to 2025
$1.9M
HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01 DK48370HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) RC2DK118640NCI NIH HHS P30 CA068485NCI NIH HHS P50 CA236733NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK048370NIDDK NIH HHS R01 DK128190NIDDK NIH HHS RC2 DK118640Volpe Foundation NA
6 · The paper itself
Abstract
Functional loss of the motor protein myosin Vb (MYO5B) induces various defects in intestinal epithelial function and causes a congenital diarrheal disorder, namely, microvillus inclusion disease (MVID). Utilizing the MVID model mice
Indexed as
Myosin Type VAnimalsCell DifferentiationDisease Models, AnimalEnterocytesEpithelial CellsIntestinal MucosaLipid MetabolismMalabsorption SyndromesMaleMiceMicrovilliMitochondriaMucolipidosesMyosin Heavy ChainsReceptors, Lysophosphatidic AcidMyo5B protein, mouseMyosin Heavy ChainsMyosin Type VReceptors, Lysophosphatidic Acidenteroidlysophosphatidic acid receptormicrovillus inclusion diseasemitochondriamouse model
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
Alterations in cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activation. · full record | Socratic